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NEURL2
Description
neuralized E3 ubiquitin protein ligase 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Molecular Function
Ubiquitin Protein Ligase Activity
Biological Process
Protein Ubiquitination
Intracellular Signal Transduction
Pathways
Neddylation
Drugs
Diseases
GWAS
Interacting Genes
7 interacting genes:
CTNNB1
ELOC
MYH6
PDCD6IP
RBX1
SMN1
UBE2H
Entrez ID
140825
HPRD ID
16353
Ensembl ID
ENSG00000124257
Uniprot IDs
Q9BR09
PDB IDs
Enriched GO Terms of Interacting Partners
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Proteolysis Involved In Protein Catabolic Process
Z Disc
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis
Cul5-RING Ubiquitin Ligase Complex
Cul2-RING Ubiquitin Ligase Complex
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Transcription Corepressor Binding
Post-translational Protein Modification
Nucleobase-containing Compound Biosynthetic Process
Cytosol
Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Glial Cell Fate Determination
Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation
Macromolecule Catabolic Process
Visceral Muscle Development
Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Mesenchymal Stem Cell Differentiation
Negative Regulation Of Canonical Wnt Signaling Pathway
Oviduct Development
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Determination Of Dorsal Identity
Negative Regulation Of Mitotic Cell Cycle, Embryonic
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Beta-catenin-ICAT Complex
Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development
Acinar Cell Differentiation
Positive Regulation Of Proteoglycan Biosynthetic Process
Fungiform Papilla Formation
Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Beta-catenin-TCF7L2 Complex
Cell-cell Junction Assembly
Astrocyte-dopaminergic Neuron Signaling
Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Metanephros Morphogenesis
Trachea Morphogenesis
Cellular Component Assembly
Bicellular Tight Junction
Regulation Of Mitotic Cell Cycle, Embryonic
Renal Inner Medulla Development
Scrib-APC-beta-catenin Complex
Regulation Of Centriole-centriole Cohesion
Renal Outer Medulla Development
Renal Vesicle Formation
Embryonic Skeletal Limb Joint Morphogenesis
RNA Metabolic Process
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