CTCFL

Gene Name		CCCTC-binding factor (zinc finger protein)-like
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Protein Binding Histone Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Cell Cycle Positive Regulation Of Gene Expression Histone Methylation DNA Methylation Involved In Gamete Generation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Histone H3-K4 Methylation
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Response to statin therapy ( 20339536) Type 2 diabetes ( 23300278)
Protein-protein Interactions		7 interactors: BAG6 BRCA1 HIST1H1A HIST1H3A HIST2H2AC PRMT7 ZDHHC17
Entrez ID		140690
HPRD ID		09512
Ensembl ID		ENSG00000124092
Uniprot IDs		A6XGM0 A6XGM9 A6XGN2 A6XGN4 Q8NI51
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression By Genetic Imprinting Regulation Of Gene Expression, Epigenetic Genetic Imprinting Chromatin Organization Chromosome Organization DNA Methylation DNA Modification Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Signal Transduction By P53 Class Mediator Nucleosome Assembly Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Positive Regulation Of Histone H3-K9 Acetylation Cellular Macromolecular Complex Assembly Gamete Generation Chromatin Assembly Organelle Organization Nucleosome Organization Chromatin Assembly Or Disassembly Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Protein-DNA Complex Assembly Sexual Reproduction Cellular Component Assembly Multicellular Organismal Reproductive Process DNA Packaging Intrinsic Apoptotic Signaling Pathway Multicellular Organism Reproduction Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Chromosome Segregation Dosage Compensation By Inactivation Of X Chromosome Tail-anchored Membrane Protein Insertion Into ER Membrane Protein K6-linked Ubiquitination Protein Insertion Into ER Membrane Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Reproduction DNA Metabolic Process Histone H4-R3 Methylation DNA Replication-dependent Nucleosome Assembly DNA Conformation Change Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Peptidyl-arginine N-methylation Regulation Of Histone H4 Acetylation
Tagcloud ?		boundaries causal compact demethylation depleted finger functionally generating h3k27me3 inactive incorporation inducer insulator insulators iptg lac laci mark modification neighbouring ones preceded removes requirement separate spreading thereby variant