SDHAF4

Description		succinate dehydrogenase complex assembly factor 4
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Enzyme Activator Activity Protein Folding Chaperone
	Biological Process	Tricarboxylic Acid Cycle Protein Folding Mitochondrial Respiratory Chain Complex II Assembly Innate Immune Response Cellular Respiration
Pathways		Maturation of TCA enzymes and regulation of TCA cycle
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: CD81 CYB5B UPK1B
Entrez ID		135154
HPRD ID		12888
Ensembl ID		ENSG00000154079
Uniprot IDs		Q5VUM1
PDB IDs		8DYD 8DYE
Enriched GO Terms of Interacting Partners?		Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Myoblast Fusion Involved In Skeletal Muscle Regeneration Apical Plasma Membrane Urothelial Plaque Nitric-oxide Synthase Complex MHC Class II Protein Binding Humoral Immune Response Mediated By Circulating Immunoglobulin Osteoclast Fusion Nitrite Reductase (NO-forming) Activity Positive Regulation Of Protein Catabolic Process In The Vacuole Positive Regulation Of T-helper 2 Cell Cytokine Production Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Tetraspanin-enriched Microdomain Positive Regulation Of Protein Exit From Endoplasmic Reticulum Transferrin Receptor Binding Positive Regulation Of Receptor Clustering Positive Regulation Of Inflammatory Response To Antigenic Stimulus Immunological Synapse Formation Regulation Of Receptor Clustering Positive Regulation Of Type 2 Immune Response Positive Regulation Of T Cell Receptor Signaling Pathway Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Regulation Of Protein Exit From Endoplasmic Reticulum Nitric Oxide Biosynthetic Process Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Alpha-beta T Cell Proliferation MHC Class II Protein Complex Binding Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Myoblast Fusion Positive Regulation Of T Cell Cytokine Production Cellular Response To Low-density Lipoprotein Particle Stimulus Nitric Oxide Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of Type 2 Immune Response Cell-cell Fusion Syncytium Formation By Plasma Membrane Fusion Cellular Response To Lipoprotein Particle Stimulus Syncytium Formation Immunoglobulin Mediated Immune Response Regulation Of T Cell Cytokine Production T Cell Costimulation B Cell Mediated Immunity Immunological Synapse Positive Regulation Of B Cell Proliferation Regulation Of Macrophage Migration Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Cholesterol Binding
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