WDR36

Description		WD repeat domain 36
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Small-subunit Processome Pwp2p-containing Subcomplex Of 90S Preribosome
	Molecular Function	RNA Binding
	Biological Process	RRNA Processing Visual Perception Ribosome Biogenesis Ribosomal Small Subunit Biogenesis
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Primary open angle glaucoma
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29785011 29083406) Allergic rhinitis ( 31361310 30013184) Allergic sensitization ( 23817571 30013184) Allergy ( 27182965) Asthma ( 31959851 30929738 31619474) Asthma (childhood onset) ( 30929738) Asthma (moderate or severe) ( 30552067) Asthma and hay fever ( 24388013) Asthma onset (childhood vs adult) ( 30929738) Childhood asthma with severe exacerbations ( 33328473) Eosinophil count ( 19198610) Eosinophilic esophagitis ( 34506852) Eosinophilic esophagitis (pediatric) ( 20208534) Medication use (antihistamines for systemic use) ( 31015401) Methadone dose in opioid dependence ( 28115739) Motor coordination ( 34177493) Periodontitis (PAL4Q3) ( 24024966) Self-reported allergy ( 23817569) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		2 interacting genes: RNF10 SUCLG1
Entrez ID		134430
HPRD ID		10305
Ensembl ID		ENSG00000134987
Uniprot IDs		Q8NI36
PDB IDs		7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Succinate-CoA Ligase Complex (ADP-forming) Succinate-CoA Ligase Complex (GDP-forming) Succinate-CoA Ligase (GDP-forming) Activity Succinate-CoA Ligase (ADP-forming) Activity Succinyl-CoA Catabolic Process Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Succinyl-CoA Metabolic Process Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Schwann Cell Proliferation Negative Regulation Of Glial Cell Proliferation Positive Regulation Of Myelination Tricarboxylic Acid Cycle Regulation Of Glial Cell Proliferation Negative Regulation Of Gliogenesis Regulation Of Myelination Postsynaptic Signal Transduction Protein Monoubiquitination Protein Autoubiquitination
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