IL31RA

Gene Name		interleukin 31 receptor A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Transcription Coactivator Activity Cytokine Receptor Activity Protein Kinase Binding Cytokine Binding
	Biological Process	MAPK Cascade Defense Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway JAK-STAT Cascade Positive Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Monocyte Differentiation Macrophage Differentiation Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Homeostatic Process Negative Regulation Of Macrophage Activation Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 23128233)
Protein-protein Interactions		2 interactors: IL6ST LIFR
Entrez ID		133396
HPRD ID		17145
Ensembl ID		ENSG00000164509
Uniprot IDs		B4DNJ2 J3KNB6 Q8NI17
PDB IDs
Enriched GO Terms of Interacting Partners?		Leukemia Inhibitory Factor Signaling Pathway Oncostatin-M-mediated Signaling Pathway Ciliary Neurotrophic Factor-mediated Signaling Pathway Interleukin-11-mediated Signaling Pathway Interleukin-27-mediated Signaling Pathway Negative Regulation Of Interleukin-6-mediated Signaling Pathway Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Positive Regulation Of Astrocyte Differentiation Response To Cytokine Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Interleukin-6-mediated Signaling Pathway Positive Regulation Of Cell Proliferation Positive Regulation Of Cardiac Muscle Hypertrophy Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Cellular Response To Interleukin-6 Positive Regulation Of Acute Inflammatory Response Regulation Of Astrocyte Differentiation Regulation Of Cardiac Muscle Hypertrophy Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Response To Interleukin-6 Positive Regulation Vascular Endothelial Growth Factor Production Negative Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Glial Cell Differentiation Negative Regulation Of Response To Cytokine Stimulus Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Cell Proliferation Positive Regulation Of Gliogenesis Glycogen Metabolic Process Positive Regulation Of JAK-STAT Cascade Regulation Of Notch Signaling Pathway Regulation Of Acute Inflammatory Response Positive Regulation Of Osteoblast Differentiation Cellular Response To Organic Substance Regulation Of Glial Cell Differentiation Polysaccharide Metabolic Process Positive Regulation Of T Cell Proliferation Regulation Of JAK-STAT Cascade Positive Regulation Of Inflammatory Response Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Ossification Regulation Of Gliogenesis Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Regulation Of Osteoblast Differentiation Response To Organic Substance Energy Reserve Metabolic Process
Tagcloud ?		ag490 bms chx concert cox2 cycloheximide extrinsic fgf13 hgf hsf igfbp4 igfbp6 igfl2 il1a il1b il1r1 il21r il6 iotal17beta iotal18 iotal19 iotal28beta mmp12 ptgs2 qrt rho stat3 substantially trail