COX4I1

Description		cytochrome c oxidase subunit 4I1
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Membrane Mitochondrial Membrane Respiratory Chain Complex IV
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Oxidative Phosphorylation Mitochondrial Electron Transport, Cytochrome C To Oxygen Response To Nutrient Cellular Respiration Proton Transmembrane Transport
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1 Mitochondrial protein degradation Complex IV assembly
Drugs		Cholic Acid N-Formylmethionine
Diseases
GWAS		Leprosy ( 25642632) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		5 interacting genes: APP MT-CO1 SDCBP TRIM55 TRIM63
Entrez ID		1327
HPRD ID		00466
Ensembl ID		ENSG00000131143
Uniprot IDs		H3BNV9 P13073 Q86WV2
PDB IDs		5Z62
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Response To Interleukin-1 Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Response To Copper Ion Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Regulation Of Receptor Internalization Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Frizzled Binding Response To Electrical Stimulus Interleukin-5 Receptor Complex Regulation Of Phosphorus Metabolic Process Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of JNK Cascade Acetylcholine Receptor Activator Activity Innate Immune Response Regulation Of Receptor-mediated Endocytosis Lipoprotein Particle Positive Regulation Of Protein Import Regulation Of Generation Of Precursor Metabolites And Energy Interleukin-5 Receptor Binding Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of JNK Cascade Defense Response To Symbiont Defense Response To Other Organism Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intracellular Signaling Cassette Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation
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