COX4I1

Gene Name		cytochrome c oxidase subunit IV isoform 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Response To Nutrient Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process Transmembrane Transport Hydrogen Ion Transmembrane Transport
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport Orphan transporters
Drugs
Diseases
GWAS		Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Protein-protein Interactions		3 interactors: APP COX1 SDCBP
Entrez ID		1327
HPRD ID		00466
Ensembl ID		ENSG00000131143
Uniprot IDs		P13073
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Positive Regulation Of Extracellular Vesicular Exosome Assembly Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Extracellular Vesicular Exosome Assembly Axon Choice Point Recognition Axon Guidance Response To Oxidative Stress Neuron Remodeling Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Substrate-dependent Cell Migration, Cell Extension Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cyclooxygenase Pathway Neuron Projection Morphogenesis Cellular Copper Ion Homeostasis Cell Morphogenesis Involved In Differentiation Prostaglandin Biosynthetic Process Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Organelle Assembly Neuron Projection Development Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Prostaglandin Metabolic Process Cell Projection Morphogenesis Cell Part Morphogenesis Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Substrate-dependent Cell Migration Neuron Recognition Neuron Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Morphogenesis Regulation Of Cell Cycle G2/M Phase Transition Icosanoid Biosynthetic Process Axon Cargo Transport Neuron Differentiation Mating Neuromuscular Junction Development
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