ZFAND2B

Description		zinc finger AN1-type containing 2B
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GO Annotations	Cellular Component	Proteasome Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Polyubiquitin Modification-dependent Protein Binding K48-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Metal Ion Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Protein Targeting To ER
Pathways
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		6 interacting genes: DAZAP2 RHOU TARDBP UBC UBQLN1 UBQLN2
Entrez ID		130617
HPRD ID		11234
Ensembl ID		ENSG00000158552
Uniprot IDs		A0A087X0D9 Q8WV99
PDB IDs		1X4V
Enriched GO Terms of Interacting Partners?		Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Molecular Condensate Scaffold Activity Cytoplasmic Stress Granule Nuclear Inner Membrane Organization Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Negative Regulation Of Store-operated Calcium Channel Activity Modification-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Autophagosome Organization Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Proteolysis Involved In Protein Catabolic Process Identical Protein Binding Organelle Assembly Interchromatin Granule Negative Regulation Of Clathrin-dependent Endocytosis Vacuole Organization Perichromatin Fibrils Regulation Of Macroautophagy Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Focal Adhesion Disassembly Endosome Membrane Macromolecule Catabolic Process Ubiquitin Protein Ligase Binding Host-mediated Suppression Of Viral Transcription Pre-mRNA Intronic Binding Autophagy Regulation Of Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Establishment Of Protein Localization Aggrephagy Proteolysis Protein Tag Activity Organelle Organization Mitogen-activated Protein Kinase Kinase Kinase Binding Host-mediated Suppression Of Viral Proces Negative Regulation Of Receptor Internalization 3'-UTR-mediated MRNA Destabilization Regulation Of Clathrin-dependent Endocytosis Regulation Of Protein Stability
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