TBC1D20

Description		TBC1 domain family member 20
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Nuclear Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Acrosome Assembly Lens Development In Camera-type Eye Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Spermatogenesis Male Gonad Development Vesicle Organization Vesicle-mediated Transport Virion Assembly Lipid Droplet Organization Camera-type Eye Development Positive Regulation Of GTPase Activity Host-mediated Activation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell Lens Fiber Cell Morphogenesis Seminiferous Tubule Development COPII-coated Vesicle Cargo Loading Regulation Of Cilium Assembly Positive Regulation Of ER To Golgi Vesicle-mediated Transport
Pathways		COPII-mediated vesicle transport TBC/RABGAPs
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917)
Interacting Genes		7 interacting genes: ADRA1A APOC2 APOC4 APP AQP6 EBP TMEM14B
Entrez ID		128637
HPRD ID		15472
Ensembl ID		ENSG00000125875
Uniprot IDs		Q96BZ9 Q9Y2V8
PDB IDs		4HL4 4HLQ
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Intermediate-density Lipoprotein Particle Low-density Lipoprotein Particle Negative Regulation Of Blood Circulation Molecular Function Activator Activity Lipoprotein Metabolic Process Acylglycerol Homeostasis Triglyceride Homeostasis Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Developmental Cell Growth Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Pilomotor Reflex Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Alpha1-adrenergic Receptor Activity Phospholipase C-activating Adrenergic Receptor Signaling Pathway Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Phospholipid Catabolic Process Lipoprotein Lipase Activator Activity Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Steroid Delta-isomerase Activity Cholestenol Delta-isomerase Activity Positive Regulation Of Synaptic Transmission Negative Regulation Of Very-low-density Lipoprotein Particle Clearance
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