DMBX1

Description		diencephalon/mesencephalon homeobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Identical Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Adult Feeding Behavior Adult Locomotory Behavior Negative Regulation Of DNA-templated Transcription Developmental Growth
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Monobrow ( 27182965) Serum uric acid levels in response to allopurinol in gout ( 25676789) Urate levels in obese individuals ( 25811787)
Interacting Genes		2 interacting genes: OTX2 UBC
Entrez ID		127343
HPRD ID		07593
Ensembl ID		ENSG00000197587
Uniprot IDs		Q8NFW5
PDB IDs
Enriched GO Terms of Interacting Partners?		Primitive Streak Formation Positive Regulation Of Embryonic Development Eukaryotic Initiation Factor 4E Binding Positive Regulation Of Gastrulation Regulation Of Gastrulation Protein Tag Activity Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Midbrain Development Dopaminergic Neuron Differentiation
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