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SHE
Gene Name
Src homology 2 domain containing E
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Molecular Function
Protein Binding
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
1 interactors:
ABL1
Entrez ID
126669
HPRD ID
17293
Ensembl ID
ENSG00000169291
Uniprot IDs
Q5VZ18
PDB IDs
Enriched GO Terms of Interacting Partners
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Transitional One Stage B Cell Differentiation
Negative Regulation Of Phospholipase C Activity
Mitochondrial Depolarization
Cellular Response To Dopamine
Actin Filament Branching
Positive Regulation Of Interferon-gamma Secretion
Collateral Sprouting
Microspike Assembly
B Cell Proliferation Involved In Immune Response
Bergmann Glial Cell Differentiation
Negative Regulation Of Phospholipase Activity
B-1 B Cell Homeostasis
Negative Regulation Of Cellular Senescence
Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Positive Regulation Of Interleukin-2 Secretion
Positive Regulation Of Osteoblast Proliferation
Positive Regulation Of Non-canonical Wnt Signaling Pathway
DNA Damage Induced Protein Phosphorylation
Negative Regulation Of Cell Aging
Immature B Cell Differentiation
Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Negative Regulation Of Lipase Activity
Cellular Response To Ammonium Ion
Regulation Of Osteoblast Proliferation
Negative Regulation Of Endothelial Cell Apoptotic Process
Regulation Of Cellular Senescence
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Cellular Response To Catecholamine Stimulus
Activated T Cell Proliferation
Regulation Of Mitochondrial Membrane Potential
Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Interleukin-2 Production
B Cell Homeostasis
Positive Regulation Of Calcium Ion Transport Into Cytosol
Peptidyl-tyrosine Autophosphorylation
Positive Regulation Of Oxidoreductase Activity
Regulation Of Actin Cytoskeleton Reorganization
Regulation Of Extracellular Matrix Organization
B Cell Receptor Signaling Pathway
Astrocyte Differentiation
B Cell Proliferation
Negative Regulation Of BMP Signaling Pathway
Spleen Development
Substrate Adhesion-dependent Cell Spreading
B Cell Activation Involved In Immune Response
Platelet-derived Growth Factor Receptor Signaling Pathway
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cerebellum Morphogenesis
Positive Regulation Of Interferon-gamma Production
Hindbrain Morphogenesis
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