CYP4F22

Description		cytochrome P450 family 4 subfamily F member 22
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Monooxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Heme Binding Metal Ion Binding
	Biological Process	Lipid Metabolic Process Icosanoid Metabolic Process Ceramide Biosynthetic Process
Pathways		Fatty acids Miscellaneous substrates Eicosanoids Synthesis of Leukotrienes (LT) and Eoxins (EX) Defective CYP4F22 causes ARCI5
Drugs
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS		Lymphocyte count ( 32888494)
Interacting Genes		4 interacting genes: AQP6 MSMO1 REEP2 TLCD4
Entrez ID		126410
HPRD ID		08256
Ensembl ID		ENSG00000171954
Uniprot IDs		Q6NT55
PDB IDs
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Taste Receptor Binding Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport C-4 Methylsterol Oxidase Activity Protein Transport Into Membrane Raft Sensory Perception Of Sweet Taste Sensory Perception Of Bitter Taste Monoatomic Anion Channel Activity Ammonium Channel Activity Renal Water Transport Protein Localization To Membrane Raft Ammonium Transmembrane Transport Endoplasmic Reticulum Water Channel Activity Carbon Dioxide Transport Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network One-carbon Compound Transport Water Transport Sensory Perception Of Taste Fluid Transport Cholesterol Biosynthetic Process Channel Activity Sterol Biosynthetic Process Cytoplasmic Microtubule Endoplasmic Reticulum Organization
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