CNGA1

Description		cyclic nucleotide gated channel subunit alpha 1
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Plasma Membrane Membrane Intracellular Cyclic Nucleotide Activated Cation Channel Complex Photoreceptor Outer Segment Membrane Rod Photoreceptor Outer Segment
	Molecular Function	Nucleotide Binding Monoatomic Ion Channel Activity Intracellularly Cyclic Nucleotide-activated Monoatomic Cation Channel Activity Intracellularly CAMP-activated Cation Channel Activity Intracellularly CGMP-activated Cation Channel Activity Calcium Channel Activity Sodium Channel Activity Protein Binding CAMP Binding CGMP Binding
	Biological Process	Monoatomic Ion Transport Sodium Ion Transport Calcium Ion Transport Visual Perception Sensory Perception Of Chemical Stimulus Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Transmembrane Transport Calcium Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport
Pathways		Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Dequalinium
Diseases		Retinitis pigmentosa (RP)
GWAS		Spondylosis ( 33332786)
Novel Interacting Genes		1 novel interacting genes: BBS7
Interacting Genes		1 interacting genes: SLC24A1
Entrez ID		1259
HPRD ID		00445
Ensembl ID		ENSG00000198515
Uniprot IDs		P29973
PDB IDs		7LFT 7LFW 7LFX 7LFY 7LG1 7RH9 7RHG 7RHH 7RHI 7RHJ 7RHK 7RHL
Enriched GO Terms of Interacting Partners?		Outer Membrane Visual Perception Sensory Perception Of Light Stimulus Calcium, Potassium:sodium Antiporter Activity Pigment Granule Aggregation In Cell Center Primary Palate Development Sensory Perception BBSome Calcium Ion Import Across Plasma Membrane Response To Light Intensity Calcium Ion Import Into Cytosol Long-term Synaptic Depression Nervous System Process Pigment Granule Localization Establishment Of Melanosome Localization Digestive Tract Morphogenesis Melanosome Localization Melanosome Transport Pigment Granule Transport Calcium Ion Import Negative Regulation Of Synaptic Transmission Long-term Synaptic Potentiation Non-motile Cilium Assembly Ciliary Membrane Limb Development System Process Heart Looping Embryonic Heart Tube Morphogenesis Photoreceptor Outer Segment Calcium Ion Transmembrane Import Into Cytosol Calcium Channel Activity Antiporter Activity Symporter Activity Inorganic Cation Import Across Plasma Membrane Smoothened Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Determination Of Bilateral Symmetry Roof Of Mouth Development Determination Of Left/right Symmetry
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