NTAN1

Description		N-terminal asparagine amidase
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GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Protein Binding Protein-N-terminal Asparagine Amidohydrolase Activity Hydrolase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Memory Adult Locomotory Behavior
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Body mass index ( 29273807) Femoral neck bone mineral density ( 22504420) Fruit consumption ( 32066663) Height ( 20189936 31562340) Metabolite levels ( 23823483) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Serum metabolite ratios in chronic kidney disease ( 29545352) Weight ( 28552196)
Novel Interacting Genes		1 novel interacting genes: NOMO1
Interacting Genes		5 interacting genes: ATE1 MEOX2 NTAQ1 UBR1 UBR2
Entrez ID		123803
HPRD ID		17649
Ensembl ID		ENSG00000157045
Uniprot IDs		A0A087X0T5 Q96AB6
PDB IDs		6A0E 6A0F 6A0H 6A0I
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway L-leucine Binding Cellular Response To L-leucine Response To L-leucine Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Arginyl-tRNA--protein Transferase Activity Negative Regulation Of TOR Signaling Cellular Response To Amino Acid Stimulus Histone H2A Ubiquitin Ligase Activity Protein-N-terminal Glutamine Amidohydrolase Activity Protein Arginylation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Ubiquitin Ligase Complex Response To Amino Acid Protein-N-terminal Asparagine Amidohydrolase Activity Protein Catabolic Process Protein Ubiquitination Protein Modification Process Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Regulation Of TOR Signaling Negative Regulation Of Nodal Signaling Pathway Somite Specification Post-translational Protein Modification Regulation Of Nodal Signaling Pathway Multi-pass Transmembrane Protein Insertion Into ER Membrane Multi-pass Translocon Complex Determination Of Left/right Asymmetry In Lateral Mesoderm Macromolecule Catabolic Process Protein Polyubiquitination Protein Targeting To Vacuole Involved In Autophagy Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Segment Specification Somite Development Proteolysis Negative Regulation Of Activin Receptor Signaling Pathway Protein K27-linked Ubiquitination Ubiquitin Protein Ligase Activity Positive Regulation Of T Cell Receptor Signaling Pathway Pattern Specification Process Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Protein Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Male Meiosis I Reciprocal Meiotic Recombination Regulation Of Activin Receptor Signaling Pathway
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