PIK3AP1

Gene Name		phosphoinositide-3-kinase adaptor protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Membrane
	Molecular Function	Phosphatidylinositol 3-kinase Regulatory Subunit Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Toll-like Receptor Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Inflammatory Response
Pathways		Signaling by the B Cell Receptor (BCR) Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: BTK GRB2 ITSN1 ITSN2 PIK3R1 SYK
Entrez ID		118788
HPRD ID		06401
Ensembl ID		ENSG00000155629
Uniprot IDs		Q6ZUJ8 Q86YV3
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Factor Import Into Nucleus Cellular Response To Molecule Of Fungal Origin Vesicle-mediated Transport Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Fc-epsilon Receptor Signaling Pathway Fc Receptor Signaling Pathway Response To Molecule Of Fungal Origin Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Activation Enzyme Linked Receptor Protein Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Lymphocyte Activation Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Positive Regulation Of Signal Transduction Antigen Receptor-mediated Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of B Cell Differentiation Positive Regulation Of Immune Response Cell Activation Platelet Activation Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Neurotrophin Signaling Pathway Leukocyte Migration Intracellular Signal Transduction Production Of Molecular Mediator Involved In Inflammatory Response Innate Immune Response Positive Regulation Of Cell-cell Adhesion Regulation Of B Cell Differentiation Regulation Of Immune Response Phagocytosis Positive Regulation Of Immune System Process Regulation Of T Cell Activation Peptidyl-tyrosine Autophosphorylation B Cell Receptor Signaling Pathway Response To Fungus Apoptotic Signaling Pathway Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Response To Organic Substance Transport Lymphocyte Activation Blood Coagulation Locomotion Hemostasis
Tagcloud ?		450k arrays cdkn2a deregulated epigenomic exome fate gabrb3 harboring hnscc hoxc12 hoxc6 inactivated mbd parp15 pax pax1 pax5 plcb1 pursued seq slco4c1 somatic throughput tsgs uncovered uppps uvulopalatopharyngoplasty zic4