AP1S1

Gene Name		adaptor-related protein complex 1, sigma 1 subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Coated Pit Membrane AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Transporter Activity
	Biological Process	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Response To Virus Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus Membrane Organization
Pathways		Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: AP1G1 AP1G2 AP1M2 AP2A2
Entrez ID		1174
HPRD ID		04635
Ensembl ID		ENSG00000106367
Uniprot IDs		P61966
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Virus Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Viral Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Intracellular Protein Transport Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Cellular Localization Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport Regulation Of Immune System Process Golgi Vesicle Transport Golgi To Vacuole Transport Endosome To Melanosome Transport Pigment Granule Maturation Cellular Pigment Accumulation Transport Immune System Process Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Regulated Secretory Pathway Melanosome Organization Pigment Granule Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Natural Killer Cell Activation Clathrin-mediated Endocytosis Regulation Of Regulated Secretory Pathway Vesicle Targeting Membrane Organization Lysosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cellular Pigmentation Positive Regulation Of Exocytosis Developmental Pigmentation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vacuolar Transport Regulation Of ERBB Signaling Pathway Ephrin Receptor Signaling Pathway
Tagcloud ?		actb api5 calculating crossbred csn1s2 fabp3 gilts icg lactation ltf mined mrpl39 mtg1 normalization parturition pcsk2 ppp2r5b primiparous ptbp1 qpcr qtrt1 rps15a scd tmem24 trim41 underscore uxt vabp vapb