KLHDC3

Name	kelch domain containing 3
Structure
Novel Interactors	3 novel interactors: DRC5 HLA-DQA1 RSPH9
Interactors	2 interactors: ENAH UBC
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytoplasm Cytosol Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Chromatin Binding Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Reciprocal Meiotic Recombination Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Meiotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Pathways	XBP1(S) activates chaperone genes
GWAS	No GWAS studies recorded
Entrez ID	116138
HPRD ID	13922
Ensembl ID	ENSG00000124702
Uniprot IDs	Q9BQ90
PDB IDs	9D1I 9D1Y 9D1Z
GO Terms Enriched among Interactors ?	Endocytic Vesicle Membrane Sperm Flagellum Cilium Movement Cilium Movement Involved In Cell Motility Radial Spoke Head 1 Radial Spoke Assembly Radial Spoke Head 3 Motile Cilium Axonemal Central Apparatus Assembly Radial Spoke Head Actin Polymerization-dependent Cell Motility Endosome Membrane MHC Class II Receptor Activity Kinocilium Profilin Binding Cell Projection Radial Spoke Peptide Antigen Assembly With MHC Class II Protein Complex Protein Tag Activity MHC Class II Protein Complex Microtubule-based Movement Cytoskeleton Postsynaptic Cytoskeleton Organization WW Domain Binding MHC Class II Protein Complex Binding Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Lumenal Side Of Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II 9+2 Motile Cilium Peptide Antigen Binding Cilium