KCTD12

Description		potassium channel tetramerization domain containing 12
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GO Annotations	Cellular Component	Plasma Membrane Membrane Presynaptic Membrane Cell Projection Receptor Complex Synapse Postsynaptic Membrane
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Incident chronic kidney disease ( 30955190) Recurrent major depressive disorder x sex interaction ( 34099189) Response to fenofibrate (triglyceride levels) ( 27002377) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		3 interacting genes: ARAP1 GABBR2 ZNF792
Entrez ID		115207
HPRD ID		11060
Ensembl ID		ENSG00000178695
Uniprot IDs		A0A140VJM4 Q96CX2
PDB IDs		6M8S 6QZL
Enriched GO Terms of Interacting Partners?		G Protein-coupled GABA Receptor Complex G Protein-coupled GABA Receptor Activity G Protein-coupled Receptor Heterodimeric Complex GABA Receptor Complex Neuron-glial Cell Signaling Type 1 Angiotensin Receptor Binding GABA Receptor Activity Negative Regulation Of Adenylate Cyclase Activity Extrinsic Component Of Plasma Membrane Positive Regulation Of Receptor Recycling Regulation Of Catalytic Activity Gamma-aminobutyric Acid Signaling Pathway Synaptic Transmission, GABAergic Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Bone Remodeling Regulation Of Filopodium Assembly Phosphatidylinositol-3,4,5-trisphosphate Binding Positive Regulation Of Filopodium Assembly Photoreceptor Cell Maintenance Negative Regulation Of Stress Fiber Assembly Regulation Of Bone Resorption Golgi Stack Multivesicular Body Podosome Regulation Of Receptor Recycling
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