TMC6

Description		transmembrane channel like 6
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Nuclear Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Binding Mechanosensitive Monoatomic Ion Channel Activity
	Biological Process	Intracellular Zinc Ion Homeostasis Monoatomic Ion Transmembrane Transport Protein Stabilization
Pathways		Neutrophil degranulation
Drugs
Diseases		Epidermodysplasia verruciformis
GWAS		Glycated hemoglobin levels ( 31213470 34059833 29170429 28887542) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin A1c levels ( 29403010) Hemoglobin levels ( 32327693) hemolysis of donated blood (cold-storage) ( 34014839) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular volume ( 27863252 32888494 29403010) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Red blood cell count ( 27863252 29403010 32888494) Red cell distribution width ( 27863252 28957414 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Serum uric acid levels ( 29559957)
Interacting Genes		3 interacting genes: CCR9 ZBTB2 ZDHHC17
Entrez ID		11322
HPRD ID		08386
Ensembl ID		ENSG00000141524
Uniprot IDs		A0A8V8TLY1 Q7Z403
PDB IDs
Enriched GO Terms of Interacting Partners?		CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Gamma-delta T Cell Differentiation Gamma-delta T Cell Activation Lipoprotein Transport Regulation Of Neurotrophin TRK Receptor Signaling Pathway Protein Palmitoylation Palmitoyltransferase Activity Regulation Of Modification Of Synaptic Structure Golgi-associated Vesicle Membrane Protein-cysteine S-palmitoyltransferase Activity Protein Lipidation
Tagcloud ?