CYP4F8

Description		cytochrome P450 family 4 subfamily F member 8
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Monooxygenase Activity Iron Ion Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Alkane 1-monooxygenase Activity Heme Binding Metal Ion Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Icosanoid Metabolic Process Prostaglandin Metabolic Process Arachidonate Metabolic Process Menaquinone Catabolic Process Phylloquinone Catabolic Process
Pathways		Fatty acids Eicosanoids Synthesis of Leukotrienes (LT) and Eoxins (EX)
Drugs
Diseases
GWAS		Inflammatory biomarkers ( 22228203)
Novel Interacting Genes		1 novel interacting genes: CD70
Interacting Genes
Entrez ID		11283
HPRD ID		08518
Ensembl ID		ENSG00000186526
Uniprot IDs		P98187
PDB IDs
Enriched GO Terms of Interacting Partners?		Adaptive Immune Memory Response CD27 Signaling Pathway Adaptive Immune Memory Response Involving T Cells And B Cells Tumor Necrosis Factor Receptor Binding B Cell Mediated Immunity T Cell Mediated Immunity B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Lymphocyte Proliferation Lymphocyte Mediated Immunity Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation T Cell Proliferation Leukocyte Proliferation Receptor Ligand Activity Positive Regulation Of T Cell Proliferation Mononuclear Cell Proliferation Extrinsic Apoptotic Signaling Pathway Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Leukocyte Mediated Immunity Positive Regulation Of Leukocyte Proliferation Regulation Of T Cell Proliferation B Cell Activation Regulation Of Mononuclear Cell Proliferation Positive Regulation Of T Cell Activation Adaptive Immune Response Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Leukocyte Proliferation T Cell Activation Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Apoptotic Signaling Pathway Positive Regulation Of Cell Activation Immune Effector Process Regulation Of T Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Cytokine-mediated Signaling Pathway Lymphocyte Activation
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