HRH3

Description		histamine receptor H3
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite Synapse Presynapse
	Molecular Function	G Protein-coupled Receptor Activity Histamine Receptor Activity Neurotransmitter Receptor Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Neurotransmitter Secretion
Pathways		Histamine receptors
Drugs		Olopatadine Aripiprazole OBE101 Histamine Betahistine Pitolisant JNJ-17216498
Diseases
GWAS		Prostate cancer ( 23535732)
Interacting Genes		3 interacting genes: ADORA2A DRD1 DRD2
Entrez ID		11255
HPRD ID		05162
Ensembl ID		ENSG00000101180
Uniprot IDs		Q9Y5N1
PDB IDs		7F61 8YN5 8YN6 8YN7 8YN8 8YUU 8YUV
Enriched GO Terms of Interacting Partners?		Synaptic Transmission, Dopaminergic Prepulse Inhibition Response To Amphetamine Presynaptic Modulation Of Chemical Synaptic Transmission Response To Amine G Protein-coupled Receptor Complex Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Amine Transport Feeding Behavior Response To Alkaloid Dopamine Neurotransmitter Receptor Activity Dopamine Binding Cerebral Cortex GABAergic Interneuron Migration Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Presynaptic Membrane Positive Regulation Of Synaptic Transmission Regulation Of Dopamine Uptake Involved In Synaptic Transmission Heterotrimeric G-protein Binding Interneuron Migration From The Subpallium To The Cortex Phospholipase C-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Urine Volume Peristalsis Locomotory Behavior Regulation Of Synaptic Plasticity Grooming Behavior Striatum Development Interneuron Migration Postsynaptic Membrane Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Behavioral Response To Cocaine Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Urine Volume Dopamine Transport Regulation Of Neurotransmitter Uptake G Protein-coupled Dopamine Receptor Signaling Pathway Response To Xenobiotic Stimulus Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Circadian Sleep/wake Cycle Chemical Synaptic Transmission Trans-synaptic Signaling Regulation Of Metal Ion Transport Synaptic Signaling G-protein Alpha-subunit Binding Monoamine Transport Dopamine Metabolic Process Non-motile Cilium G Protein-coupled Receptor Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Adult Walking Behavior Regulation Of Synaptic Transmission, GABAergic
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