MAP4K5

Gene Name		mitogen-activated protein kinase kinase kinase kinase 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity Protein Binding ATP Binding
	Biological Process	Protein Phosphorylation Activation Of JUN Kinase Activity Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 20125193)
Protein-protein Interactions		12 interactors: ABL1 BCR COPS5 CRK CRKL GRB2 HCK NEDD4 SETDB1 TANK TRAF2 ZNF440
Entrez ID		11183
HPRD ID		05374
Ensembl ID		ENSG00000012983
Uniprot IDs		B3KWC4 Q9Y4K4
PDB IDs
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Signaling Pathway Regulation Of Immune Response Regulation Of MAPK Cascade Positive Regulation Of Immune Response Regulation Of Intracellular Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Immune Response Regulation Of Immune System Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Innate Immune Response Immune System Process Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Response To Organic Substance Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Endocytosis Regulation Of Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Defense Response Regulation Of Actin Cytoskeleton Organization Regulation Of Signaling Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Metabolic Process Cell Surface Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Vesicle-mediated Transport Regulation Of Actin Filament-based Process Regulation Of Phosphorus Metabolic Process Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Metabolic Process Positive Regulation Of MAPK Cascade Response To Stress Cellular Response To Organonitrogen Compound Regulation Of Cytoskeleton Organization Positive Regulation Of Innate Immune Response Regulation Of Endocytosis Protein K63-linked Ubiquitination Intracellular Signal Transduction Signal Transduction Positive Regulation Of Interleukin-2 Production Protein Autophosphorylation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway
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