LILRB4

Gene Name		leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Antigen Binding Receptor Activity Protein Binding
	Biological Process	Immune System Process Signal Transduction Negative Regulation Of Osteoclast Differentiation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		3 interactors: INPP5D PTPN11 PTPN6
Entrez ID		11006
HPRD ID		11996
Ensembl ID		ENSG00000186818
Uniprot IDs		Q8NHJ6
PDB IDs		3P2T
Enriched GO Terms of Interacting Partners?		Abortive Mitotic Cell Cycle Leukocyte Migration Megakaryocyte Development Positive Regulation Of Cell Activation Platelet Formation Platelet Morphogenesis Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Megakaryocyte Differentiation Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of B Cell Differentiation Regulation Of Lymphocyte Activation Blood Coagulation Hemostasis Dephosphorylation Immune Response-regulating Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Cell Activation Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Body Fluid Levels Wound Healing Response To Wounding Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Leukocyte Proliferation T Cell Costimulation Cell Migration Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Immune Response Positive Regulation Of Immune System Process Cell Motility Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Immune Response Negative Regulation Of Lymphocyte Activation Antigen Receptor-mediated Signaling Pathway Cellular Response To Interferon-gamma Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Regulation Of Lymphocyte Differentiation Negative Regulation Of Signaling Negative Regulation Of Leukocyte Activation Response To Interferon-gamma Locomotion Peptidyl-tyrosine Dephosphorylation Immune Response Regulation Of Immune System Process
Tagcloud ?		atp6v0d2 ctsk gcgr gpnmb granuloma instillation intratracheal lpo marco mmp12 mmp7 mreg mt3 nanotube nanotubes padi1 persistence persistently rnase9 slc26a4 spp1 subchronic suspensions swcnt swcnts tnfsf4 toxicological trem2 upregulated