SPINK5

Name	serine peptidase inhibitor Kazal type 5
Structure
Interactors	1 interactors: PRSS1
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Cell Cortex Perinuclear Region Of Cytoplasm Epidermal Lamellar Body
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity
	Biological Process	Negative Regulation Of Antibacterial Peptide Production Epidermal Cell Differentiation Negative Regulation Of Angiogenesis Cell Differentiation Regulation Of Cell Adhesion Extracellular Matrix Organization Epithelial Cell Differentiation Hair Cell Differentiation Regulation Of T Cell Differentiation Negative Regulation Of Proteolysis Negative Regulation Of Immune Response Regulation Of Timing Of Anagen
Pathways	Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Diseases	Netherton syndrome
GWAS	Blood protein levels ( 30072576 )
Entrez ID	11005
HPRD ID	05423
Ensembl ID	ENSG00000133710
Uniprot IDs	Q9NQ38
PDB IDs	1H0Z 1HDL 1UUC 1UVF 1UVG 5YHN
GO Terms Enriched among Interactors ?	Digestion Extracellular Matrix Disassembly Serine-type Peptidase Activity Serine-type Endopeptidase Activity Blood Microparticle Extracellular Structure Organization Extracellular Matrix Organization