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METAP2
Gene Name
methionyl aminopeptidase 2
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Molecular Function
Aminopeptidase Activity
Metalloexopeptidase Activity
Poly(A) RNA Binding
Metal Ion Binding
Metalloaminopeptidase Activity
Biological Process
Proteolysis
Phototransduction, Visible Light
Rhodopsin Mediated Signaling Pathway
Protein Processing
Peptidyl-methionine Modification
Regulation Of Rhodopsin Mediated Signaling Pathway
N-terminal Protein Amino Acid Modification
Protein Initiator Methionine Removal
Pathways
Inactivation, recovery and regulation of the phototransduction cascade
Visual phototransduction
The phototransduction cascade
Diseases associated with visual transduction
Drugs
L-Methionine
3,5,6,8-Tetramethyl-N-Methyl Phenanthrolinium
Fumagillin
D-Methionine
N\'-(2s,3r)-3-Amino-4-Cyclohexyl-2-Hydroxy-Butano-N-(4-Methylphenyl)Hydrazide
(E)-(2r,3r,4s,5r)-3,4,5-Trihydroxy-2-Methoxy-8,8-Dimethyl-Non-6-Enoic Acid ((3s,6r)-6-Hydroxy-2-Oxo-Azepan-3-Yl)-Amide
2-Methyl-2-Propanol
(2s,3r)-3-Amino-2-Hydroxy-5-(Ethylsulfanyl)Pentanoyl-((S)-(-)-(1-Naphthyl)Ethyl)Amide
Ovalicin
5-BROMO-2-{[(4-CHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID
5-METHYL-2-[(PHENYLSULFONYL)AMINO]BENZOIC ACID
2-[(PHENYLSULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID
2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID
N\'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE
3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID
(CHLOROACETYL)CARBAMIC ACID (3R,4S,5S,5R)-5-METHOXY-4-[(2R,3R)-2-METHYL-3-(3-METHYL-2-BUTENYL)OXIRANYL]-1-OXASPIRO[2.5]OCT-6-YL ESTER
Diseases
GWAS
Protein-protein Interactions
10 interactors:
APP
CALM1
CDC42
EIF2AK2
EIF2S3
HMGA1
MAPK1
MAPK3
RAC1
S100A4
Entrez ID
10988
HPRD ID
03522
Ensembl ID
ENSG00000111142
Uniprot IDs
B4DUX5
F8VQZ7
G3XA91
P50579
PDB IDs
1B59
1B6A
1BN5
1BOA
1KQ0
1KQ9
1QZY
1R58
1R5G
1R5H
1YW7
1YW8
1YW9
2ADU
2EA2
2EA4
2GA2
2OAZ
Enriched GO Terms of Interacting Partners
?
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Kinase Activity
Innate Immune Response
Blood Coagulation
Hemostasis
Platelet Activation
Positive Regulation Of Kinase Activity
Positive Regulation Of Transferase Activity
Regulation Of Protein Phosphorylation
Regulation Of Body Fluid Levels
Fc Receptor Signaling Pathway
Response To External Stimulus
Wound Healing
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Response To Wounding
Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Protein Phosphorylation
Immune Response
Regulation Of Phosphorylation
Regulation Of Protein Kinase Activity
Defense Response
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Axon Guidance
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cellular Amino Acid Metabolic Process
Regulation Of Phosphorus Metabolic Process
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Positive Regulation Of Phosphorylation
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Catalytic Activity
Positive Regulation Of Protein Modification Process
Positive Regulation Of Cellular Biosynthetic Process
Immune Response-regulating Signaling Pathway
Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Cellular Metabolic Process
Regulation Of Golgi Inheritance
Regulation Of Cellular Ketone Metabolic Process
Axonogenesis
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Signal Transduction
Caveolin-mediated Endocytosis
Cell Morphogenesis
Viral Process
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Axon Development
Tagcloud
?
aiming
aip
alignment
boar
brms1
chordc1
clues
cops6
csde1
csfv
ddx5
domestic
fever
gnb2l1
hemorrhagic
hspa8
interactive
nav1
ncbi
ns5a
phf5a
polr1c
ppp2r3c
psmc3
suvec
swine
tmed10
tmem70
y2h