CFHR4

Gene Name		complement factor H-related 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region
	Molecular Function	Lipid Transporter Activity
	Biological Process	Lipid Transport
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23577725 23536807) Age-related macular degeneration (extreme sampling) ( 23577725) End-stage coagulation ( 23381943) Nephropathy ( 21399633)
Protein-protein Interactions		2 interactors: C3 CDC42
Entrez ID		10877
HPRD ID		05627
Ensembl ID		ENSG00000134365
Uniprot IDs		Q5DVJ7 Q92496
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Type IIa Hypersensitivity Regulation Of Lipid Metabolic Process Actin Filament Branching Submandibular Salivary Gland Formation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Activation Of Membrane Attack Complex Establishment Of Golgi Localization Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Hypersensitivity Positive Regulation Of Apoptotic Cell Clearance Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Protein Heterodimerization Activity Positive Regulation Of Immune Response Keratinocyte Development Regulation Of Synapse Structural Plasticity Regulation Of Apoptotic Cell Clearance Positive Regulation Of Protein Phosphorylation Complement Activation, Alternative Pathway Positive Regulation Of Inflammatory Response To Antigenic Stimulus Positive Regulation Of Transport Positive Regulation Of Pseudopodium Assembly Nuclear Migration Cardiac Conduction System Development Golgi Localization Innate Immune Response Positive Regulation Of Humoral Immune Response Positive Regulation Of Phosphorylation Regulation Of Immune Response Filopodium Assembly Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Hair Follicle Placode Formation Positive Regulation Of Protein Processing Regulation Of Triglyceride Biosynthetic Process Macrophage Differentiation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Dendritic Cell Migration Regulation Of Protein Phosphorylation Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Of Nucleus Localization Positive Regulation Of Acute Inflammatory Response Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Complement Activation
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