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SIX2
Gene Name
SIX homeobox 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Plasma Membrane
Nuclear Membrane
Molecular Function
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Factor Binding
Protein Complex Binding
Sequence-specific DNA Binding
Biological Process
Kidney Development
Chondrocyte Differentiation
Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Protein Import Into Nucleus
Mesodermal Cell Fate Specification
Cell Proliferation
Anatomical Structure Morphogenesis
Anterior/posterior Axis Specification
Cell Migration
Regulation Of Ossification
Regulation Of Chondrocyte Differentiation
Middle Ear Morphogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Embryonic Digestive Tract Morphogenesis
Embryonic Cranial Skeleton Morphogenesis
Nephron Development
Nephron Morphogenesis
Mesenchymal Stem Cell Maintenance Involved In Nephron Morphogenesis
Mesenchymal Cell Differentiation Involved In Kidney Development
Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Mesenchymal Stem Cell Proliferation
Positive Regulation Of Chondrocyte Proliferation
Pathways
Drugs
Diseases
GWAS
Metabolite levels (
21909109
)
Protein-protein Interactions
5 interactors:
AES
APP
EYA1
EYA3
TLE1
Entrez ID
10736
HPRD ID
05408
Ensembl ID
ENSG00000170577
Uniprot IDs
Q8TBA2
Q9NPC8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Histone Dephosphorylation
Regulation Of Anoikis
Anatomical Structure Morphogenesis
Positive Regulation Of DNA Repair
RNA Metabolic Process
Response To Radiation
Gene Expression
Regulation Of DNA Repair
Positive Regulation Of Response To DNA Damage Stimulus
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Response To DNA Damage Stimulus
Multicellular Organismal Development
Notch Signaling Pathway
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Response To Ionizing Radiation
Regulation Of Protein Binding
Positive Regulation Of DNA Metabolic Process
Double-strand Break Repair
Regulation Of Gene Expression
Anatomical Structure Development
Synaptic Growth At Neuromuscular Junction
Regulation Of Nitrogen Compound Metabolic Process
Transcription, DNA-templated
Cellular Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Peptidyl-tyrosine Dephosphorylation
Collateral Sprouting In Absence Of Injury
Negative Regulation Of Wnt Signaling Pathway
Developmental Process
Organ Morphogenesis
Nitrogen Compound Metabolic Process
Positive Regulation Of Secondary Heart Field Cardioblast Proliferation
Positive Regulation Of Anoikis
Regulation Of Signal Transduction
Negative Regulation Of Signal Transduction
Response To Abiotic Stimulus
Collateral Sprouting
Axon Midline Choice Point Recognition
Protein Dephosphorylation
Neurological System Process
Negative Regulation Of Signaling
Organ Development
Regulation Of Binding
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Tagcloud
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amphiphysin
bmp7
bred
cited1
e13
e15
endowment
ensures
eya1
gammah2ax
hypo
lhx1
mdm
mesenchyme
metanephroi
nephrogenic
nephron
npc
organogenesis
patchy
pax2
pax8
pockets
renewing
sall1
superficially
susceptibile
thinning
wnt4