CERS1

Description		ceramide synthase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	N-acyltransferase Activity Transferase Activity Sphingosine N-acyltransferase Activity
	Biological Process	Lipid Metabolic Process Sphingolipid Metabolic Process Brain Development Negative Regulation Of Cardiac Muscle Hypertrophy Sphingolipid Biosynthetic Process Cellular Response To Mycotoxin Negative Regulation Of D-glucose Import Ceramide Biosynthetic Process Cellular Response To Xenobiotic Stimulus Cellular Response To UV-A Cellular Response To Dithiothreitol Positive Regulation Of Mitophagy
Pathways		Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: BDKRB1 DRD2 HTR4 LTB4R2 MAPK6
Entrez ID		10715
HPRD ID		12114
Ensembl ID		ENSG00000223802
Uniprot IDs		B4DE47 P27544 Q5XG75
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Blood Pressure Cell Migration Signal Transduction Regulation Of Blood Pressure Regulation Of Sequestering Of Calcium Ion Cell Motility Bradykinin Receptor Activity Negative Regulation Of Synaptic Transmission, Glutamatergic Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Response To Histamine Regulation Of Synapse Structural Plasticity Dopamine Binding Regulation Of Renal Sodium Excretion Dopamine Neurotransmitter Receptor Activity Regulation Of Synapse Organization Cerebral Cortex GABAergic Interneuron Migration Chemical Synaptic Transmission Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway G Protein-coupled Receptor Complex Catecholamine Uptake Dopamine Uptake Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Adenohypophysis Development Negative Regulation Of Dephosphorylation Response To Inactivity Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Negative Regulation Of Neuron Migration Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Neuron-neuron Synaptic Transmission Interneuron Migration From The Subpallium To The Cortex Branching Morphogenesis Of A Nerve Negative Regulation Of Dopamine Secretion Peristalsis Regulation Of Body Fluid Levels Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Neurotransmitter Uptake Regulation Of Dopamine Uptake Involved In Synaptic Transmission Heterotrimeric G-protein Binding Regulation Of Locomotion Involved In Locomotory Behavior Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Urine Volume
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