GNLY

Description		granulysin
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytolytic Granule Phagocytic Vesicle Lumen
	Molecular Function	Protein Binding
	Biological Process	Cellular Defense Response Killing Of Cells Of Another Organism Defense Response To Bacterium Defense Response To Fungus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		Antimicrobial peptides
Drugs		3-(N-morpholino)propanesulfonic acid
Diseases
GWAS
Interacting Genes		4 interacting genes: APP BCL2L1 DERL3 FBXO7
Entrez ID		10578
HPRD ID		01788
Ensembl ID		ENSG00000115523
Uniprot IDs		B4E3H9 P22749
PDB IDs		1L9L
Enriched GO Terms of Interacting Partners?		Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Protein Localization Regulation Of Neuron Apoptotic Process Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Signaling Pathway Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Apoptotic Process In Bone Marrow Cell Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Protein Localization Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Dendritic Cell Proliferation Dendritic Cell Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Lewy Body Core Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Cell Cycle Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Response To Cycloheximide Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway
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