GPNMB

Gene Name		glycoprotein (transmembrane) nmb
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane Melanosome
	Molecular Function	Integrin Binding Heparin Binding
	Biological Process	Osteoblast Differentiation Cell Adhesion Negative Regulation Of Cell Proliferation Bone Mineralization
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: ITSN2 SMAD4
Entrez ID		10457
HPRD ID		05081
Ensembl ID		ENSG00000136235
Uniprot IDs		F5GY20 F6SKP1 Q14956 Q96F58
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Nephrogenic Mesenchyme Morphogenesis Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Endocardial Cell Differentiation Formation Of Anatomical Boundary Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Endothelial Cell Activation Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Valve Formation Sebaceous Gland Development Somite Rostral/caudal Axis Specification Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Brainstem Development SMAD Protein Complex Assembly Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Canal Development Regulation Of Hair Follicle Development Heart Valve Formation Metanephric Mesenchyme Development Endocardial Cushion Formation Endocardium Development Atrioventricular Valve Morphogenesis Regulation Of Hair Cycle Endocardial Cushion Morphogenesis Atrioventricular Valve Development Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Heart Morphogenesis Positive Regulation Of Epithelial To Mesenchymal Transition Heart Valve Morphogenesis Heart Valve Development Endocardial Cushion Development Positive Regulation Of Signal Transduction Positive Regulation Of BMP Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Embryonic Axis Specification Positive Regulation Of Stem Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Epithelial To Mesenchymal Transition Gastrulation With Mouth Forming Second Regulation Of Epithelial To Mesenchymal Transition SMAD Protein Signal Transduction Branching Involved In Ureteric Bud Morphogenesis Regulation Of Epidermis Development Anterior/posterior Axis Specification Ureteric Bud Morphogenesis Somatic Stem Cell Maintenance Endothelial Cell Differentiation
Tagcloud ?		atp6v0d2 ctsk gcgr granuloma instillation intratracheal lilrb4 lpo marco mmp12 mmp7 mreg mt3 nanotube nanotubes padi1 persistence persistently rnase9 slc26a4 spp1 subchronic suspensions swcnt swcnts tnfsf4 toxicological trem2 upregulated