LYPLA1

Gene Name		lysophospholipase I
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Vesicular Exosome
	Molecular Function	Lysophospholipase Activity Palmitoyl-(protein) Hydrolase Activity
	Biological Process	Protein Depalmitoylation Fatty Acid Metabolic Process Negative Regulation Of Golgi To Plasma Membrane Protein Transport Small Molecule Metabolic Process Nitric Oxide Metabolic Process Regulation Of Nitric-oxide Synthase Activity
Pathways		eNOS activation Metabolism of nitric oxide eNOS activation and regulation
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: ANXA2 GOLGA2
Entrez ID		10434
HPRD ID		07063
Ensembl ID		ENSG00000120992
Uniprot IDs		B4DP64 O75608 Q6IAQ1
PDB IDs		1FJ2
Enriched GO Terms of Interacting Partners?		Regulation Of Binding Osteoclast Development Membrane Raft Assembly Protein Heterotetramerization Fibrinolysis Membrane Raft Organization Positive Regulation Of Vesicle Fusion Membrane Assembly Membrane Biogenesis Protein Targeting To Plasma Membrane Regulation Of Vesicle Fusion Negative Regulation Of Blood Coagulation Osteoclast Differentiation Negative Regulation Of Coagulation Collagen Fibril Organization Positive Regulation Of Fibroblast Proliferation Negative Regulation Of Wound Healing Negative Regulation Of Protein Binding Establishment Of Protein Localization To Plasma Membrane Membrane Budding Regulation Of Fibroblast Proliferation Regulation Of Blood Coagulation Body Fluid Secretion Negative Regulation Of Binding Protein Tetramerization Positive Regulation Of Binding Myeloid Leukocyte Differentiation Regulation Of Wound Healing Protein Heterooligomerization Protein Localization To Plasma Membrane Regulation Of Protein Binding Protein Targeting To Membrane
Tagcloud ?		abpp advance campaign carbamate depalmitoylation dual fluopol hras hts irreversible micromolar ml211 ml348 ml349 ml378 optimized owing palmitoyl palmitoylation polarization sar scaffold seeking solubility thioesterase triazole