RAPGEF3

Gene Name		Rap guanine nucleotide exchange factor (GEF) 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane CAMP-dependent Protein Kinase Complex Endomembrane System Membrane Extracellular Vesicular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity Rap Guanyl-nucleotide Exchange Factor Activity CAMP Binding
	Biological Process	Angiogenesis Energy Reserve Metabolic Process Signal Transduction Blood Coagulation Cell Proliferation CAMP-mediated Signaling Platelet Activation Positive Regulation Of CAMP Catabolic Process Rap Protein Signal Transduction Positive Regulation Of Rap GTPase Activity Small Molecule Metabolic Process Positive Regulation Of Angiogenesis Regulation Of Protein Kinase Activity Regulation Of Insulin Secretion Positive Regulation Of Stress Fiber Assembly Establishment Of Endothelial Barrier Cellular Response To CAMP Regulation Of Actin Cytoskeleton Reorganization
Pathways		Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Rap1 signalling Integration of energy metabolism Regulation of insulin secretion Integrin alphaIIb beta3 signaling Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation) Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: AP2B1 MAP1A PNMA1 RAP1A RAP2A RRAS2
Entrez ID		10411
HPRD ID		06928
Ensembl ID		ENSG00000079337
Uniprot IDs		O95398 Q99777
PDB IDs
Enriched GO Terms of Interacting Partners?		Rap Protein Signal Transduction Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction
Tagcloud ?