AKR1A1

Gene Name		aldo-keto reductase family 1, member A1 (aldehyde reductase)
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytosol Apical Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Alditol:NADP+ 1-oxidoreductase Activity Electron Carrier Activity L-glucuronate Reductase Activity
	Biological Process	Glucose Metabolic Process Cellular Aldehyde Metabolic Process L-ascorbic Acid Biosynthetic Process D-glucuronate Catabolic Process Aldehyde Catabolic Process Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: EXOSC4 TERF1 TERF2IP
Entrez ID		10327
HPRD ID		00069
Ensembl ID		ENSG00000117448
Uniprot IDs		P14550
PDB IDs		2ALR
Enriched GO Terms of Interacting Partners?		Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process DNA Metabolic Process Negative Regulation Of DNA Recombination At Telomere Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening DNA Replication Telomere Maintenance Via Telomere Shortening Regulation Of Cellular Component Organization Protection From Non-homologous End Joining At Telomere Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Nuclear MRNA Surveillance RNA Surveillance DNA Deamination Histone MRNA Catabolic Process Replicative Cell Aging Negative Regulation Of Telomerase Activity Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Microtubule Polymerization Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Telomerase Activity Maturation Of 5.8S RRNA Histone MRNA Metabolic Process Negative Regulation Of DNA Recombination Negative Regulation Of DNA Biosynthetic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Regulation Of Double-strand Break Repair Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Microtubule Polymerization Protein Localization To Chromosome RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Mitotic Spindle Assembly Checkpoint Regulation Of Organelle Organization Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Chromosome Organization Regulation Of DNA Biosynthetic Process
Tagcloud ?		acceptors akr1c4 akrs aldo amplify catalyze catechols causation deoxyguanosine dihydrodiols diol dione epoxide exacerbating futile keto michael mutagen mutagenicity oxidoreductases pah promiscuous pyrene quinone quinones reductases reminiscent transversions