GDF11

Gene Name		growth differentiation factor 11
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Extracellular Space
	Molecular Function	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Growth Factor Activity
	Biological Process	Skeletal System Development Metanephros Development Ureteric Bud Development Nervous System Development Mesoderm Development Negative Regulation Of Cell Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Spinal Cord Anterior/posterior Patterning Pancreas Development Growth Regulation Of Apoptotic Process Regulation Of MAPK Cascade Negative Regulation Of Cell Differentiation Cell Development Cell Maturation Camera-type Eye Morphogenesis Palate Development SMAD Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: ACVR2B
Entrez ID		10220
HPRD ID		04895
Ensembl ID		ENSG00000135414
Uniprot IDs		O95390
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Activin Receptor Signaling Pathway Lymphatic Endothelial Cell Differentiation Lymphangiogenesis Lymph Vessel Morphogenesis Venous Blood Vessel Development Retina Vasculature Development In Camera-type Eye Regulation Of Activin Receptor Signaling Pathway Lymph Vessel Development Embryonic Foregut Morphogenesis Foregut Morphogenesis Activin Receptor Signaling Pathway Positive Regulation Of Bone Mineralization Insulin Secretion Positive Regulation Of Biomineral Tissue Development Blood Vessel Remodeling Gastrulation With Mouth Forming Second Artery Development Peptide Hormone Secretion Peptide Secretion Digestive Tract Morphogenesis Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation BMP Signaling Pathway Endothelial Cell Differentiation Hormone Secretion Endothelium Development Hormone Transport Peptide Transport Pancreas Development Positive Regulation Of Ossification Organ Growth Odontogenesis Of Dentin-containing Tooth Palate Development Determination Of Left/right Symmetry Tissue Remodeling Determination Of Bilateral Symmetry Protein Secretion Regulation Of Osteoblast Differentiation Amide Transport Response To Glucose Odontogenesis Digestive Tract Development Post-embryonic Development Mesoderm Development Digestive System Development Retina Development In Camera-type Eye Response To Carbohydrate Gastrulation Regulation Of Ossification Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?		ace activin actriib anemia cotreatment epo erythrocyte erythroid erythropoiesis erythropoietic erythropoietin ex hyperplasia iib implicate ineffective late maturation potently precursors progressively rap smad2 superfamily synergistic transforming trapping unlike version