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ACOT8
Gene Name
acyl-CoA thioesterase 8
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrion
Peroxisomal Matrix
Molecular Function
Receptor Binding
Protein Binding
Palmitoyl-CoA Hydrolase Activity
Choloyl-CoA Hydrolase Activity
Acyl-CoA Hydrolase Activity
Carboxylic Ester Hydrolase Activity
Medium-chain Acyl-CoA Hydrolase Activity
Biological Process
Acyl-CoA Metabolic Process
Bile Acid Biosynthetic Process
Bile Acid Metabolic Process
Viral Process
Peroxisome Fission
Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Unsaturated Fatty Acid Metabolic Process
Alpha-linolenic Acid Metabolic Process
Dicarboxylic Acid Catabolic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Pathways
Beta-oxidation of pristanoyl-CoA
Bile acid and bile salt metabolism
alpha-linolenic acid (ALA) metabolism
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Metabolism of lipids and lipoproteins
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Synthesis of bile acids and bile salts
Beta-oxidation of very long chain fatty acids
Peroxisomal lipid metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions
2 interactors:
PEX5
REL
Entrez ID
10005
HPRD ID
06998
Ensembl ID
ENSG00000101473
Uniprot IDs
E9PRD4
O14734
PDB IDs
Enriched GO Terms of Interacting Partners
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Negative Regulation Of Protein Homotetramerization
Protein Import Into Peroxisome Matrix, Translocation
Protein Import Into Peroxisome Matrix, Docking
Negative Regulation Of Protein Homooligomerization
Protein Import Into Peroxisome Membrane
Protein To Membrane Docking
Peroxisomal Membrane Transport
Negative Regulation Of Protein Oligomerization
Positive Regulation Of Interleukin-12 Biosynthetic Process
Protein Import Into Peroxisome Matrix
Regulation Of Interleukin-12 Biosynthetic Process
Protein Targeting To Peroxisome
Establishment Of Protein Localization To Peroxisome
Very Long-chain Fatty Acid Metabolic Process
Cerebral Cortex Neuron Differentiation
Regulation Of Protein Oligomerization
NIK/NF-kappaB Signaling
Endoplasmic Reticulum Organization
Fatty Acid Beta-oxidation
Peroxisome Organization
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Multicellular Organism Growth
Intracellular Protein Transmembrane Transport
Mitochondrial Membrane Organization
I-kappaB Kinase/NF-kappaB Signaling
Protein Transmembrane Transport
Fatty Acid Oxidation
Lipid Oxidation
Fatty Acid Catabolic Process
Regulation Of Interleukin-12 Production
Positive Regulation Of Cytokine Biosynthetic Process
Cerebral Cortex Cell Migration
Membrane Docking
Regulation Of Multicellular Organism Growth
Telencephalon Cell Migration
Forebrain Cell Migration
Protein Tetramerization
Regulation Of Cytokine Biosynthetic Process
Neuromuscular Process
Negative Regulation Of Protein Complex Assembly
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