CD47 and TAGLN3

		CD47	TAGLN3
Description		CD47 molecule	transgelin 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Nucleus Actin Cytoskeleton Synapse
	Molecular Function	Protein Binding Fibrinogen Binding Thrombospondin Receptor Activity Protein Binding Involved In Heterotypic Cell-cell Adhesion Cell-cell Adhesion Mediator Activity	Protein Binding Actin Filament Binding
	Biological Process	Angiogenesis Positive Regulation Of Immune System Process Apoptotic Process Inflammatory Response Cell Adhesion Integrin-mediated Signaling Pathway Positive Regulation Of Cell Population Proliferation Cell Migration Positive Regulation Of Cell-cell Adhesion Regulation Of Type II Interferon Production Regulation Of Interleukin-10 Production Regulation Of Interleukin-12 Production Regulation Of Interleukin-6 Production Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Inflammatory Response Negative Regulation Of Phagocytosis Positive Regulation Of Phagocytosis Positive Regulation Of T Cell Activation Positive Regulation Of Stress Fiber Assembly Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Type II Interferon Cellular Response To Interleukin-1 Cellular Response To Interleukin-12 Cell-cell Adhesion ATP Export Positive Regulation Of Monocyte Extravasation	Negative Regulation Of Transcription By RNA Polymerase II Actin Filament Organization Central Nervous System Development
Pathways		Cell surface interactions at the vascular wall Integrin cell surface interactions Signal regulatory protein family interactions Signal regulatory protein family interactions Neutrophil degranulation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756 33263727 34002096) Body mass index ( 25673413) Refractive error ( 32231278) Regular attendance at a religious group ( 29970889)
Interacting Genes		25 interacting genes: BNIP3 EPB42 FAS GAP43 GNAI1 IGF2BP2 IGSF8 ITGAV MAP3K10 MTIF3 MUC1 P2RY2 PLA1A PTK2 PVR RHAG SIRPA SRC SYNE4 TAGLN3 TFEB THBS1 TMEM167B UBQLN1 ZBTB20	1 interacting genes: CD47
Entrez ID		961	29114
HPRD ID		03017	12136
Ensembl ID		ENSG00000196776	ENSG00000144834
Uniprot IDs		A0A0A1TSG4 Q08722	Q9UI15
PDB IDs		2JJS 2JJT 2VSC 4CMM 4KJY 5IWL 5TZ2 5TZT 5TZU 7MYZ 7WN8 7XJF 7YGG 8RP8
Enriched GO Terms of Interacting Partners?		Response To Mechanical Stimulus Regulation Of Apoptotic Signaling Pathway Cellular Response To Stress Signaling Receptor Activity Ankyrin-1 Complex Integrin Binding Signal Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Catabolic Process Cellular Response To Hydrogen Peroxide Positive Regulation Of Phosphate Metabolic Process Regulation Of Focal Adhesion Assembly Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Cell-substrate Junction Organization Regulation Of Proteolysis Negative Regulation Of Programmed Cell Death Positive Regulation Of Fibroblast Migration Positive Regulation Of Metabolic Process Response To Hyperoxia Response To Hydrogen Peroxide Filopodium Membrane Negative Regulation Of Transport Transforming Growth Factor Beta Binding Fibroblast Growth Factor Binding Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Integrin-mediated Signaling Pathway Positive Regulation Of Phosphorylation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Macrophage Chemotaxis Negative Regulation Of Anoikis Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Glycolytic Process Cellular Response To Reactive Oxygen Species Cell Motility Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Chemical Stress Multicellular Organismal-level Iron Ion Homeostasis Symbiont Entry Into Host Cell Protein Autophosphorylation Positive Regulation Of Macrophage Migration Regulation Of Anoikis Autophagy Fibronectin Binding Regulation Of Cell Adhesion Extracellular Matrix Binding Regulation Of Cell-matrix Adhesion	Protein Binding Involved In Heterotypic Cell-cell Adhesion Positive Regulation Of Monocyte Extravasation Cellular Response To Interleukin-12 ATP Export Response To Interleukin-12 Thrombospondin Receptor Activity Fibrinogen Binding Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Cellular Extravasation ATP Transport Negative Regulation Of Phagocytosis Cell-cell Adhesion Mediator Activity Nucleotide Transport Regulation Of Cellular Extravasation Adenine Nucleotide Transport Purine Nucleotide Transport Heterotypic Cell-cell Adhesion Cellular Response To Interleukin-1 Positive Regulation Of Stress Fiber Assembly Regulation Of Interleukin-10 Production Regulation Of Nitric Oxide Metabolic Process Regulation Of Interleukin-12 Production Regulation Of Nitric Oxide Biosynthetic Process Tertiary Granule Membrane Positive Regulation Of Actin Filament Bundle Assembly Negative Regulation Of Endocytosis Positive Regulation Of Phagocytosis Carbohydrate Derivative Transport Cellular Response To Type II Interferon Response To Interleukin-1 Specific Granule Membrane Positive Regulation Of Mononuclear Cell Migration Response To Type II Interferon Regulation Of Phagocytosis Regulation Of Stress Fiber Assembly Integrin-mediated Signaling Pathway Regulation Of Type II Interferon Production Organophosphate Ester Transport Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Regulation Of Interleukin-6 Production Positive Regulation Of Endocytosis Positive Regulation Of Supramolecular Fiber Organization Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Inflammatory Response Positive Regulation Of Cytoskeleton Organization Nucleobase-containing Compound Transport Regulation Of Leukocyte Migration Regulation Of Actin Filament Organization Positive Regulation Of T Cell Activation
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