HNRNPLL and DDX39A

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		HNRNPLL	DDX39A
Description		heterogeneous nuclear ribonucleoprotein L like	DExD-box helicase 39A
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GO Annotations	Cellular Component	Nucleus Membrane Synapse Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Speck
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Identical Protein Binding
	Biological Process	MRNA Processing Positive Regulation Of RNA Splicing Regulation Of RNA Splicing	MRNA Splicing, Via Spliceosome Toll-like Receptor Signaling Pathway Cytoplasmic Pattern Recognition Receptor Signaling Pathway MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing Negative Regulation Of Innate Immune Response Negative Regulation Of RNA Export From Nucleus
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Body mass index ( 28892062)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		67 interacting genes: ADAMTSL4 ATXN1 BANP BARD1 BCAS2 BHLHE40 BOLL CALCOCO2 CEBPA DAB1 DDX39A DDX39B DENND2D DHX57 EFHC2 EIF4ENIF1 FAM9B GOPC GTF2A1 HNRNPK HOOK1 IKZF3 KHDRBS2 KRT31 KRT40 KRTAP10-3 MAGED1 MAP4K3 MDFI MID2 MREG NRG2 OTOF PAXIP1 PCBP1 PCBP3 PNMA1 POLR1F PRPF6 PRSS8 PTBP1 QKI RBM10 RBM3 RBPMS REL RHOXF2 SKIL SNRPA SPRY2 SRSF11 SRSF7 SSX2IP SUMO2 TADA2A THAP1 TLE5 TMCC2 TMEM178A TRIM23 TRIM27 TRIM29 UBE2I USP10 VAC14 WEE2-AS1 ZNF311	14 interacting genes: CCL14 CEBPA DDX39B EXOSC9 HIPK2 HNRNPLL PTK2 RNF4 SARNP SAT1 SUMO2 TERF1 TERF2IP UBE2I
Entrez ID		92906	10212
HPRD ID		13667	10861
Ensembl ID		ENSG00000143889	ENSG00000123136
Uniprot IDs		A0A0S2Z6K1 A8K894 Q8WVV9	O00148
PDB IDs		7EVS	8IJU
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding Identical Protein Binding RNA Binding Regulation Of MRNA Processing MRNA Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Regulation Of MRNA Metabolic Process MRNA Processing RNA Splicing Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process PML Body MRNA Metabolic Process Nucleus Regulation Of RNA Splicing Regulation Of Transcription By RNA Polymerase II Nuclear Speck RNA Processing Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Splicing Nucleic Acid Metabolic Process Regulation Of Gene Expression Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Response To Cytokine Response To Peptide Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Metabolic Process SUMO Transferase Activity Regulation Of Metabolic Process Spliceosomal Complex Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process MRNA Stabilization Nuclear Export Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process	PML Body Regulation Of Ubiquitin-dependent Protein Catabolic Process Nuclear Body Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping G-rich Strand Telomeric DNA Binding Transcription Export Complex Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Primary Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process SUMO Transferase Activity RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomerase Nuclear Export Regulation Of Proteolysis Nucleus Nuclear Chromosome Presynaptic Cytosol Postsynaptic Cytosol Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Positive Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Telomere Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Proteolysis Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Protein Metabolic Process RNA Binding Spermidine Binding Protein Sumoylation Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly SUMO Conjugating Enzyme Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Regulation Of Metabolic Process Nuclear Transport Nucleocytoplasmic Transport Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process
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