PDLIM7 and NUDT10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PDLIM7	NUDT10
Description		PDZ and LIM domain 7	nudix hydrolase 10
Image
GO Annotations	Cellular Component	Stress Fiber Ruffle Nucleoplasm Cytoplasm Cytosol Cytoskeleton Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Filamentous Actin	Nucleus Cytoplasm Cytosol
	Molecular Function	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding	Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Pyrophosphatase Activity Hydrolase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity Metal Ion Binding
	Biological Process	Ossification Receptor-mediated Endocytosis Heart Development Actin Cytoskeleton Organization Cell Differentiation Muscle Structure Development	Diphosphoinositol Polyphosphate Metabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process
Pathways		RET signaling	Synthesis of pyrophosphates in the cytosol
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Age at first birth ( 34211149) Prostate cancer ( 18264097 18264098)
Interacting Genes		64 interacting genes: ABI2 AP5B1 ATOSB BAG3 BSG CATSPER1 CCDC185 CDK12 DDX6 DGCR6 DNER ENKD1 FAM90A1 FNDC11 FRS3 GARIN6 GEM GFAP GPATCH2L HEY2 HNRNPD HNRNPF HSF2BP HSPB7 IL16 IQGAP1 KANK2 MDM2 NUDT10 OTUD6A PAK5 PARVG PCBP1 PHF1 PIN1 PLEKHN1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RASGEF1B RET RPP25 SCNM1 SH2B2 SH3BP2 SLAIN1 SMURF1 SNCA SPP1 TCF19 TNPO2 TP53 TPM2 TRAF2 TRAF3 TSG101 TSGA10IP UBE2I UBQLN4 WWP2 ZMYND11 ZNF165	8 interacting genes: HSF2BP MTUS2 PDLIM7 RASSF1 REL SNAPC5 TCF4 TRIM8
Entrez ID		9260	170685
HPRD ID		10436	17651
Ensembl ID		ENSG00000196923	ENSG00000122824
Uniprot IDs		Q9NR12	Q8NFP7
PDB IDs		2Q3G 7RM8	3MCF
Enriched GO Terms of Interacting Partners?		Protein Binding Diacylglycerol-dependent Serine/threonine Kinase Activity Histone H3T6 Kinase Activity Striated Muscle Cell Apoptotic Process Cellular Response To Actinomycin D Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Muscle Cell Apoptotic Process Response To Actinomycin D Protein Kinase C Signaling Cellular Response To UV-C Regulation Of MAPK Cascade Signaling Adaptor Activity Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Transport Regulation Of Protein Metabolic Process Regulation Of Chaperone-mediated Autophagy Regulation Of Programmed Cell Death Histone H3K36me3 Reader Activity Actin Filament Apoptotic Process Regulation Of Gene Expression Cytoplasmic Side Of Plasma Membrane Supramolecular Fiber Organization Negative Regulation Of Catabolic Process Enzyme Binding Programmed Cell Death Negative Regulation Of Signal Transduction Regulation Of Apoptotic Process Cellular Response To Antibiotic Cell Death Negative Regulation Of Programmed Cell Death Mitotic Nuclear Membrane Disassembly Negative Regulation Of Glial Cell Apoptotic Process Thioesterase Binding CD40 Receptor Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?