IL32 and KPNA5

Number of citations of the paper that reports this interaction (PubMedID 25178676)
0

Data Source:
BioGRID (two hybrid)

		IL32	KPNA5
Description		interleukin 32	karyopherin subunit alpha 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol NLS-dependent Protein Nuclear Import Complex
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Defense Response Immune Response Cell Adhesion Signal Transduction Positive Regulation Of Gene Expression Positive Regulation Of Type III Interferon Production Negative Regulation Of Viral Life Cycle	Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Protein Transport
Pathways		Other interleukin signaling RAC3 GTPase cycle	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) HIV-1 susceptibility ( 22174851) Liver enzyme levels (alanine transaminase) ( 33972514)	Early cardiac repolarization ( 31600170) Telomere length ( 21460395)
Interacting Genes		12 interacting genes: C1QB HSPA8 IFT140 KPNA5 NDN NQO2 PRTN3 RHBDD2 RPL4 SNRNP70 TUT1 ZFPM2	29 interacting genes: ANP32A ANP32B ARNT ATM ATOSB BRMS1 CDKN1B CFTR DCPS EPAS1 FBXO7 HIF1A HNRNPC IL32 KAT5 LMNB1 MLH1 NMNAT1 NRF1 POLR3C POU6F2 RAD52 RBBP4 SPOP SPOPL TSEN54 TWIST1 WT1 ZNF326
Entrez ID		9235	3841
HPRD ID		09346	05179
Ensembl ID		ENSG00000008517	ENSG00000196911
Uniprot IDs		C6GKH1 G3LU47 P24001	A0A8V8TL88 A0A8V8TMV2 O15131
PDB IDs			4U2X
Enriched GO Terms of Interacting Partners?			Nucleoplasm Nucleus Negative Regulation Of DNA Metabolic Process Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Regulation Of DNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Developmental Process Positive Regulation Of Catabolic Process Regulation Of Gene Expression Regulation Of Multicellular Organismal Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Multicellular Organismal Process DNA Double-strand Break Processing Embryonic Placenta Development Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Apoptotic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macroautophagy Cellular Response To Stress Negative Regulation Of Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Developmental Process Chromatin Negative Regulation Of Double-strand Break Repair Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA Repair MRNA Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Developmental Process Histone Deacetylase Binding Regulation Of Protein Modification Process Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation DNA Damage Response, Signal Transduction By P53 Class Mediator Chromatin Remodeling Negative Regulation Of DNA Recombination Positive Regulation Of Hormone Biosynthetic Process DNA-binding Transcription Factor Activity
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