RAB11B and RAB11FIP3

Number of citations of the paper that reports this interaction (PubMedID 11481332)
0

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		RAB11B	RAB11FIP3
Description		RAB11B, member RAS oncogene family	RAB11 family interacting protein 3
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GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Cytosol Synaptic Vesicle Membrane Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane Extracellular Exosome	Golgi Membrane Nucleoplasm Cytoplasm Mitochondrion Endosome Golgi Apparatus Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Endosome Membrane Membrane Endocytic Vesicle Midbody Cytoplasmic Vesicle Membrane Endocytic Vesicle Membrane Cleavage Furrow Trans-Golgi Network Membrane Centriolar Satellite Ciliary Basal Body Intercellular Bridge Recycling Endosome Recycling Endosome Membrane Bounding Membrane Of Organelle Postsynaptic Recycling Endosome Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Myosin V Binding Cadherin Binding	Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Metal Ion Binding GTPase Binding Dynein Light Intermediate Chain Binding Molecular Adaptor Activity
	Biological Process	Receptor Recycling Protein Transport Melanosome Transport Endocytic Recycling Transferrin Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Monoatomic Anion Transport Constitutive Secretory Pathway Regulated Exocytosis Cellular Response To Acidic PH Establishment Of Protein Localization To Membrane Vesicle-mediated Transport To The Plasma Membrane Amyloid-beta Clearance By Transcytosis Regulation Of Protein Localization To Cell Surface Regulation Of Endocytic Recycling	Mitotic Cytokinesis Vesicle Docking Involved In Exocytosis Microtubule-based Movement Vesicle-mediated Transport Endocytic Recycling Regulation Of Cytokinesis Golgi To Plasma Membrane Protein Transport Positive Regulation Of Cilium Assembly Cell Division Regulation Of Vesicle-mediated Transport Early Endosome To Recycling Endosome Transport Protein Localization To Cilium Negative Regulation Of Adiponectin Secretion Regulation Of Cilium Assembly Regulation Of Early Endosome To Recycling Endosome Transport Positive Regulation Of Mitotic Cytokinetic Process Regulation Of Protein Localization To Centrosome Protein Localization To Cleavage Furrow Regulation Of Endocytic Recycling
Pathways		TBC/RABGAPs RAB geranylgeranylation	VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494)	Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 27863252 32888494) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 32888494)
Interacting Genes		12 interacting genes: APP IKBKG MEOX2 MYO5B OPTN PRKG2 RAB11FIP2 RAB11FIP3 RAB11FIP5 SNCA SREBF2 TYK2	10 interacting genes: ARF4 ARF5 ARF6 ASAP1 IFT140 RAB11A RAB11B RAB11FIP4 RAB25 TOMM34
Entrez ID		9230	9727
HPRD ID		05009	18521
Ensembl ID		ENSG00000185236	ENSG00000090565
Uniprot IDs		Q15907	O75154
PDB IDs		2F9L 2F9M 4OJK	2D7C 2HV8 4D0M 4UJ3 4UJ4
Enriched GO Terms of Interacting Partners?		Recycling Endosome Regulation Of Protein Localization Recycling Endosome Membrane Negative Regulation Of Adiponectin Secretion Vesicle-mediated Transport Cytoplasmic Vesicle Membrane Positive Regulation Of Protein Localization Negative Regulation Of Transport Establishment Of Localization In Cell Insulin Secretion Involved In Cellular Response To Glucose Stimulus Small GTPase Binding Regulated Exocytosis Identical Protein Binding Regulation Of Amyloid-beta Clearance Regulation Of Neurotransmitter Uptake Endosome Regulation Of Autophagy Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Cellular Response To Copper Ion Negative Regulation Of Secretion By Cell Regulation Of Receptor Recycling K63-linked Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Small Molecule Metabolic Process Amyloid Fibril Formation Signal Release Endocytosis Microglial Cell Activation Positive Regulation Of Defense Response Negative Regulation Of Secretion Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Response To Copper Ion Negative Regulation Of Signaling Negative Regulation Of Cell Communication Leukocyte Activation Involved In Inflammatory Response Protein Localization To Plasma Membrane Golgi To Plasma Membrane Protein Transport Regulation Of Macroautophagy Polyubiquitin Modification-dependent Protein Binding Exocytosis Regulation Of Transport Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Localization Positive Regulation Of Catabolic Process Protein Localization To Cell Periphery Insulin Secretion Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion	GTPase Activity GTP Binding Protein Localization To Cilium Golgi Apparatus G Protein Activity Endocytic Recycling Myosin V Binding Recycling Endosome Membrane Intracellular Protein Localization Vesicle-mediated Transport Intracellular Transport Vesicle-mediated Transport To The Plasma Membrane Recycling Endosome Protein Localization To Cleavage Furrow Establishment Of Protein Localization Positive Regulation Of Epithelial Cell Migration Plasma Membrane Bounded Cell Projection Organization Cleavage Furrow Cellular Localization Establishment Of Localization In Cell Regulation Of Cell Projection Assembly Positive Regulation Of Mitotic Cytokinetic Process Amyloid-beta Clearance By Transcytosis Regulation Of Epithelial Cell Migration Protein Transport Endosomal Transport Cell Projection Organization Regulation Of Cytokinesis Protein Localization To Organelle Regulation Of Cilium Assembly Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Transcytosis Regulation Of Endocytic Recycling Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Melanosome Localization Pigment Granule Localization Amyloid-beta Clearance Regulation Of Cell Division Protein Localization To Cell Surface Nucleotide Binding Localization Within Membrane Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Exocytosis Regulation Of Protein Localization To Cell Surface
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