RAB11FIP3

Description		RAB11 family interacting protein 3
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GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Cytoplasm Mitochondrion Endosome Golgi Apparatus Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Endosome Membrane Membrane Endocytic Vesicle Midbody Cytoplasmic Vesicle Membrane Endocytic Vesicle Membrane Cleavage Furrow Trans-Golgi Network Membrane Centriolar Satellite Ciliary Basal Body Intercellular Bridge Recycling Endosome Recycling Endosome Membrane Bounding Membrane Of Organelle Postsynaptic Recycling Endosome Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Metal Ion Binding GTPase Binding Dynein Light Intermediate Chain Binding Molecular Adaptor Activity
	Biological Process	Mitotic Cytokinesis Vesicle Docking Involved In Exocytosis Microtubule-based Movement Vesicle-mediated Transport Endocytic Recycling Regulation Of Cytokinesis Golgi To Plasma Membrane Protein Transport Positive Regulation Of Cilium Assembly Cell Division Regulation Of Vesicle-mediated Transport Early Endosome To Recycling Endosome Transport Protein Localization To Cilium Negative Regulation Of Adiponectin Secretion Regulation Of Cilium Assembly Regulation Of Early Endosome To Recycling Endosome Transport Positive Regulation Of Mitotic Cytokinetic Process Regulation Of Protein Localization To Centrosome Protein Localization To Cleavage Furrow Regulation Of Endocytic Recycling
Pathways		VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 27863252 32888494) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 32888494)
Novel Interacting Genes		10 novel interacting genes: ARF4 ARF5 ARF6 ASAP1 IFT140 RAB11A RAB11B RAB11FIP4 RAB25 TOMM34
Interacting Genes		10 interacting genes: ARF4 ARF5 ARF6 ASAP1 IFT140 RAB11A RAB11B RAB11FIP4 RAB25 TOMM34
Entrez ID		9727
HPRD ID		18521
Ensembl ID		ENSG00000090565
Uniprot IDs		O75154
PDB IDs		2D7C 2HV8 4D0M 4UJ3 4UJ4
Enriched GO Terms of Interacting Partners?		GTPase Activity GTP Binding Protein Localization To Cilium Golgi Apparatus G Protein Activity Endocytic Recycling Myosin V Binding Recycling Endosome Membrane Intracellular Protein Localization Vesicle-mediated Transport Intracellular Transport Vesicle-mediated Transport To The Plasma Membrane Recycling Endosome Protein Localization To Cleavage Furrow Establishment Of Protein Localization Positive Regulation Of Epithelial Cell Migration Plasma Membrane Bounded Cell Projection Organization Cleavage Furrow Cellular Localization Establishment Of Localization In Cell Regulation Of Cell Projection Assembly Positive Regulation Of Mitotic Cytokinetic Process Amyloid-beta Clearance By Transcytosis Regulation Of Epithelial Cell Migration Protein Transport Endosomal Transport Cell Projection Organization Regulation Of Cytokinesis Protein Localization To Organelle Regulation Of Cilium Assembly Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Transcytosis Regulation Of Endocytic Recycling Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Melanosome Localization Pigment Granule Localization Amyloid-beta Clearance Regulation Of Cell Division Protein Localization To Cell Surface Nucleotide Binding Localization Within Membrane Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Exocytosis Regulation Of Protein Localization To Cell Surface
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