AP4M1 and ZBTB22

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		AP4M1	ZBTB22
Description		adaptor related protein complex 4 subunit mu 1	zinc finger and BTB domain containing 22
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Membrane AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Extracellular Exosome	Chromatin Nucleus
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity Protein Domain Specific Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Autophagosome Assembly Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Golgi To Endosome Transport Intracellular Protein Localization Protein Transport Vesicle-mediated Transport Protein Transmembrane Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane	Regulation Of Transcription By RNA Polymerase II
Pathways		Lysosome Vesicle Biogenesis
Drugs
Diseases		Cerebral palsy
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Autism spectrum disorder or schizophrenia ( 28540026) Walking pace ( 33128006)
Interacting Genes		17 interacting genes: ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B HOOK1 HOOK2 KRTAP5-2 LAMP2 PMPCB TGOLN2 USP47 ZBTB22	16 interacting genes: AP4M1 CCDC13 DNAJA3 DRC4 FXR2 GABARAPL1 GATA1 MCRS1 MEMO1 MLLT6 PIN1 RBM39 TCEA2 UBQLN4 VAPA VAPB
Entrez ID		9179	9278
HPRD ID		03803	15761
Ensembl ID		ENSG00000221838	ENSG00000236104
Uniprot IDs		C9JC87 C9JWL4 H7C0A0 O00189	A0A1U9X8V3 O15209
PDB IDs		3L81 4MDR
Enriched GO Terms of Interacting Partners?		Postsynaptic Density Membrane Ligand-gated Monoatomic Ion Channel Activity Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission, Glutamatergic Ligand-gated Ion Channel Signaling Pathway Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential FHF Complex Synaptic Transmission, Glutamatergic Intracellular Protein Localization Platelet Dense Granule Membrane Glutamate Receptor Signaling Pathway NMDA Glutamate Receptor Activity Protein Localization To Perinuclear Region Of Cytoplasm Excitatory Postsynaptic Potential NMDA Selective Glutamate Receptor Complex Glutamate-gated Calcium Ion Channel Activity Calcium Ion Transmembrane Transport Regulation Of Synaptic Plasticity Excitatory Chemical Synaptic Transmission Cellular Localization Regulation Of Synaptic Transmission, Glutamatergic Monoatomic Ion Transmembrane Transport Calcium Ion Transport HOPS Complex Modulation Of Chemical Synaptic Transmission Somatodendritic Compartment Regulation Of Postsynaptic Membrane Potential Monoatomic Ion Transport Lysosomal Transport Inorganic Cation Transmembrane Transport Early Endosome To Late Endosome Transport Monoatomic Cation Transmembrane Transport AMPA Glutamate Receptor Complex Dynein Light Intermediate Chain Binding Positive Regulation Of Synaptic Transmission Late Endosome Protein Localization To Postsynaptic Membrane Positive Regulation Of Excitatory Postsynaptic Potential Inorganic Ion Transmembrane Transport Protein Localization To Postsynapse Transmembrane Transport Monoatomic Ion Channel Activity Vacuolar Transport Monoatomic Cation Transport Trans-Golgi Network Mitotic Cleavage Furrow Ingression Pigment Granule Maturation Peptide Pheromone Maturation Chaperone-mediated Autophagy Translocation Complex Establishment Of Protein Localization	FFAT Motif Binding COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Endoplasmic Reticulum Localization Host-mediated Activation Of Viral Genome Replication Host-mediated Perturbation Of Viral Genome Replication Host-mediated Suppression Of Viral Genome Replication Organelle Organization Ciliary Basal Body Centriolar Satellite Viral Release From Host Cell Endoplasmic Reticulum Exit Site Vesicle Budding From Membrane Protein-membrane Adaptor Activity Host-mediated Activation Of Viral Process Beta-tubulin Binding Cis-trans Isomerase Activity
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