RASL10B and NDUFS3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RASL10B	NDUFS3
Description		RAS like family 10 member B	NADH:ubiquinone oxidoreductase core subunit S3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Nuclear Body Mitochondrial Membrane Respiratory Chain Complex I
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Atrial Natriuretic Peptide Positive Regulation Of Peptide Hormone Secretion	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Substantia Nigra Development Mitochondrial Respiratory Chain Complex I Assembly Proton Motive Force-driven Mitochondrial ATP Synthesis Reactive Oxygen Species Metabolic Process Proton Transmembrane Transport
Pathways			Respiratory electron transport Complex I biogenesis RHOG GTPase cycle Mitochondrial protein degradation
Drugs			NADH
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321)	Adult body size ( 32376654) Alcohol use disorder (total score) ( 30336701) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 20935630) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Fruit consumption ( 32066663) Height ( 28552196) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mood instability ( 31168069) Neuroticism ( 29255261) Refractive error ( 32231278) Sleep duration (short sleep) ( 30846698)
Interacting Genes		11 interacting genes: AKT1 APP BAG4 CFTR FGFR2 FGFR4 NDUFS3 NEDD4L PARP1 PAX2 TSG101	3 interacting genes: GZMA RASL10B TMEM11
Entrez ID		91608	4722
HPRD ID		15215	10355
Ensembl ID		ENSG00000270885	ENSG00000213619
Uniprot IDs		Q96S79	O75489
PDB IDs			5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Cellular Response To Growth Factor Stimulus Regulation Of Protein Localization Response To Growth Factor Response To Nerve Growth Factor Regulation Of Membrane Potential Positive Regulation Of Developmental Process Positive Regulation Of Protein Localization Response To Lipid Cellular Response To Nerve Growth Factor Stimulus Fibroblast Growth Factor Receptor Activity Cellular Response To Oxygen-containing Compound Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Vesicle-mediated Transport Response To Alcohol Regulation Of Growth Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Intracellular Signal Transduction Regulation Of Developmental Growth Protein-folding Chaperone Binding Regulation Of Small Molecule Metabolic Process Protein Homodimerization Activity Negative Regulation Of CGAS/STING Signaling Pathway Positive Regulation Of Fibroblast Migration Protein Autophosphorylation Protein-containing Complex Endosome Cellular Developmental Process Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Enzyme Binding Epithelial Cell Differentiation Fibroblast Growth Factor Binding Regulation Of Monoatomic Ion Transport Positive Regulation Of Transport Regulation Of Protein Localization To Nucleus Chemical Homeostasis Heparin Binding Axonogenesis Morphogenesis Of Embryonic Epithelium Positive Regulation Of Developmental Growth Positive Regulation Of Endocytosis Cellular Response To Lipid Cellular Response To Metal Ion Positive Regulation Of Signal Transduction 14-3-3 Protein Binding Positive Regulation Of ERK1 And ERK2 Cascade Epithelial Tube Formation Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Developmental Process	Negative Regulation Of Deoxyribonuclease Activity Negative Regulation Of Endodeoxyribonuclease Activity Cytotoxic T Cell Pyroptotic Cell Death Regulation Of Systemic Arterial Blood Pressure By Atrial Natriuretic Peptide Negative Regulation Of Nuclease Activity Negative Regulation Of Oxidoreductase Activity Regulation Of Endodeoxyribonuclease Activity Granzyme-mediated Programmed Cell Death Signaling Pathway Negative Regulation Of DNA Binding Pyroptotic Cell Death Regulation Of Oxidoreductase Activity Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal
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