YIF1B and LTB4R2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		YIF1B	LTB4R2
Description		Yip1 interacting factor homolog B, membrane trafficking protein	leukotriene B4 receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Nucleoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding	Leukotriene B4 Receptor Activity G Protein-coupled Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Protein Targeting To Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Cilium Assembly Sperm Flagellum Assembly	Chemotaxis Signal Transduction G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Keratinocyte Migration Leukotriene Signaling Pathway
Pathways			Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Leukotriene B4
Diseases
GWAS			Anorectal malformation ( 31136621) Height ( 28552196)
Interacting Genes		6 interacting genes: AKT1 B9D2 GPR35 GPR37 LTB4R2 LXN	48 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MUC1 MYO1E OBSL1 P4HTM PER1 PIGM PKD1 PTGIS RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B
Entrez ID		90522	56413
HPRD ID		11277	16153
Ensembl ID		ENSG00000167645	ENSG00000213906
Uniprot IDs		Q5BJH7 Q9H5F7	B4E292 Q9NPC1
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Signaling Pathway G Protein-coupled Peptide Receptor Activity Response To Rapamycin Positive Regulation Of Protein Localization To Endoplasmic Reticulum Nitric-oxide Synthase Regulator Activity Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Negative Regulation Of SREBP Signaling Pathway Response To Insulin-like Growth Factor Stimulus Response To Temperature Stimulus Negative Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of TORC2 Signaling TRNA Stabilization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Potassium Channel Activator Activity Mammalian Oogenesis Stage RNA (guanine-N7)-methylation Ameboidal-type Cell Migration Negative Regulation Of Fatty Acid Transport Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Cellular Response To Peptide Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Maintenance Of Protein Location In Mitochondrion TRNA (guanine-N7)-methylation Activation-induced Cell Death Of T Cells Regulation Of Long-chain Fatty Acid Import Into Cell TORC2 Complex Binding Cellular Response To Rapamycin Peripheral Nervous System Myelin Maintenance Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Deoxyribonuclease Activity Negative Regulation Of Protein Localization To Lysosome Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Regulation Of TRNA Methylation Positive Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Transmembrane Transport SREBP-SCAP Complex Retention In Endoplasmic Reticulum C-X-C Chemokine Receptor Activity G Protein-coupled Receptor Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Neuropeptide Signaling Pathway Prosaposin Receptor Activity Positive Regulation Of Dopamine Metabolic Process Locomotion Involved In Locomotory Behavior Leukotriene Signaling Pathway Keratinocyte Migration Leukotriene B4 Receptor Activity Leukotriene Receptor Activity	Endoplasmic Reticulum Membrane Endoplasmic Reticulum Membrane Extracellular Exosome Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Vesicle Oligosaccharyltransferase Complex B
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