KLC4 and KATNAL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		KLC4	KATNAL1
Description		kinesin light chain 4	katanin catalytic subunit A1 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Kinesin Complex Microtubule	Spindle Pole Cytoplasm Mitochondrion Centrosome Spindle Cytosol Cytoskeleton Microtubule Katanin Complex Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	Protein Binding Kinesin Binding	Nucleotide Binding Protein Binding ATP Binding Microtubule Binding Microtubule Severing ATPase Activity Isomerase Activity ATP Hydrolysis Activity Identical Protein Binding
	Biological Process	Microtubule-based Movement	Spermatogenesis Cytoplasmic Microtubule Organization Microtubule Severing
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Blood osmolality (transformed sodium) ( 28360221) Fat distribution (HIV) ( 21897333) Femur bone mineral density x serum urate levels interaction ( 34046847) Male-pattern baldness ( 27182965) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928) Refractive error ( 32231278) Type 2 diabetes ( 31049640)
Interacting Genes		33 interacting genes: ABI3 AKAP9 APP CASK CEP57 CEP57L1 COIL DDX6 DRC5 KATNAL1 KPNA2 KRT13 KRT15 KRT16 KRT31 KRT33B KRT34 MEOX2 NDEL1 NECAB2 PCM1 PDE4DIP PKP2 PRC1 RBM14 SERTAD1 SLC16A9 TADA2A TSC1 USHBP1 YWHAE YWHAZ ZNF343	18 interacting genes: AIRIM ASCC2 BYSL CEP57L1 CFTR COX17 CTNNA3 GCC1 GUCA1A IQUB KATNBL1 KLC4 MEOX2 PGAM2 PITPNC1 SIAH1 VPS4B ZNF69
Entrez ID		89953	84056
HPRD ID		13932	13753
Ensembl ID		ENSG00000137171	ENSG00000102781
Uniprot IDs		Q9NSK0	B3KUK7 Q9BW62
PDB IDs			6B5C
Enriched GO Terms of Interacting Partners?		Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Cytoskeleton Organization Intermediate Filament Cytoskeleton Keratin Filament Organelle Organization Structural Molecule Activity Tissue Morphogenesis Microtubule-based Process Morphogenesis Of An Epithelium Anatomical Structure Morphogenesis Phosphoserine Residue Binding Identical Protein Binding Regulation Of Heart Rate By Cardiac Conduction Epithelial Cell Differentiation Cardiac Conduction Microtubule Binding Transmembrane Transporter Binding Epidermis Development Neuron Migration Microtubule Cytoskeleton Organization Centrosome Cytoplasmic Microtubule Organization Hair Cycle Protein Binding Molecular Adaptor Activity Microtubule Regulation Of Golgi Organization Microtubule Organizing Center Organization Developmental Process Microtubule Organizing Center Structural Constituent Of Cytoskeleton Regulation Of Heart Rate Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Blood Circulation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Localization Cytosol Concave Side Of Sperm Head Maintenance Of Protein Localization At Cell Tip Memory T Cell Differentiation Positive Regulation Of Microtubule Polymerization
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