KLC4 and ZNF343

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KLC4	ZNF343
Description		kinesin light chain 4	zinc finger protein 343
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Kinesin Complex Microtubule	Nucleus
	Molecular Function	Protein Binding Kinesin Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Microtubule-based Movement	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Generic Transcription Pathway
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693)	Conotruncal heart defects (maternal effects) ( 28468790) Glomerular filtration rate in chronic kidney disease ( 26420894)
Interacting Genes		33 interacting genes: ABI3 AKAP9 APP CASK CEP57 CEP57L1 COIL DDX6 DRC5 KATNAL1 KPNA2 KRT13 KRT15 KRT16 KRT31 KRT33B KRT34 MEOX2 NDEL1 NECAB2 PCM1 PDE4DIP PKP2 PRC1 RBM14 SERTAD1 SLC16A9 TADA2A TSC1 USHBP1 YWHAE YWHAZ ZNF343	25 interacting genes: ACTN3 APP BFSP2 CCDC125 FAM90A1 FASTKD5 HUNK JRK KLC4 NEK6 NME7 NUDT22 NXF1 PAX9 RAD51D RUNX1T1 SDCBP STK16 TEPSIN TRIM41 UBQLN1 USP20 ZNF319 ZNF648 ZNF835
Entrez ID		89953	79175
HPRD ID		13932	18327
Ensembl ID		ENSG00000137171	ENSG00000088876
Uniprot IDs		Q9NSK0	A0A087WZQ2 Q6P1L6
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Cytoskeleton Organization Intermediate Filament Cytoskeleton Keratin Filament Organelle Organization Structural Molecule Activity Tissue Morphogenesis Microtubule-based Process Morphogenesis Of An Epithelium Anatomical Structure Morphogenesis Phosphoserine Residue Binding Identical Protein Binding Regulation Of Heart Rate By Cardiac Conduction Epithelial Cell Differentiation Cardiac Conduction Microtubule Binding Transmembrane Transporter Binding Epidermis Development Neuron Migration Microtubule Cytoskeleton Organization Centrosome Cytoplasmic Microtubule Organization Hair Cycle Protein Binding Molecular Adaptor Activity Microtubule Regulation Of Golgi Organization Microtubule Organizing Center Organization Developmental Process Microtubule Organizing Center Structural Constituent Of Cytoskeleton Regulation Of Heart Rate Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Blood Circulation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Localization Cytosol Concave Side Of Sperm Head Maintenance Of Protein Localization At Cell Tip Memory T Cell Differentiation Positive Regulation Of Microtubule Polymerization
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