FOXH1 and SOX14

Data Source:
BioGRID (two hybrid)

		FOXH1	SOX14
Description		forkhead box H1	SRY-box transcription factor 14
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Activin Responsive Factor Complex	Chromatin Cellular_component Nucleus Transcription Regulator Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding SMAD Binding Androgen Receptor Binding Co-SMAD Binding R-SMAD Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Heart Looping Secondary Heart Field Specification Outflow Tract Morphogenesis Cardiac Right Ventricle Morphogenesis Ventricular Trabecula Myocardium Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Embryonic Heart Tube Anterior/posterior Pattern Specification Aorta Morphogenesis Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Axial Mesoderm Development Negative Regulation Of Androgen Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Nervous System Development Visual Perception Entrainment Of Circadian Clock Anatomical Structure Morphogenesis Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Neuron Migration
Pathways		Signaling by NODAL Signaling by Activin
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Educational attainment ( 25201988) General cognitive ability ( 29844566)	Alzheimer's disease in APOE e4- carriers ( 25778476) Glucocorticoid-induced osteonecrosis ( 26265699)
Interacting Genes		67 interacting genes: AOC1 ARID5A ATP23 ATXN1L BATF2 C10orf55 C11orf1 C19orf54 CEACAM6 CRX CRYBA1 CYSRT1 DAZAP2 DRAP1 FAM168B FAM83A FOXD2 FOXG1 HDHD3 HEY1 HLX HOXA1 HSF4 KLHL26 KRTAP11-1 KRTAP13-3 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP7-1 LASP1 MAGED1 MGAT5B MSX2 NKX2-5 NOTO OXER1 PLA2G10 PNMA5 PPP1R37 PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 RBM46 RBPMS2 RNF144B SERGEF SMAD2 SMAD3 SMAD4 SOX14 SOX4 TEKT5 TFG TLX3 TSC1 UBAP2 UFSP1 ZC3H10 ZIC1 ZNF34 ZNF503	9 interacting genes: CRX FOXH1 KRTAP15-1 NAIF1 ROR2 TEX37 TRIM54 VENTX ZDHHC17
Entrez ID		8928	8403
HPRD ID		04689	16067
Ensembl ID		ENSG00000160973	ENSG00000168875
Uniprot IDs		O75593	O95416
PDB IDs		5XOC
Enriched GO Terms of Interacting Partners?
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