NAPA and GOSR1

Number of citations of the paper that reports this interaction (PubMedID 8636227)
44

Data Source:
HPRD (in vitro, in vivo)

		NAPA	GOSR1
Description		NSF attachment protein alpha	golgi SNAP receptor complex member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Neuromuscular Junction Presynaptic Active Zone Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Exosome Presynapse Postsynapse Glutamatergic Synapse	Golgi Membrane Golgi Apparatus Golgi Medial Cisterna Cis-Golgi Network Cytosol Membrane Transport Vesicle SNARE Complex
	Molecular Function	SNARE Binding Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding Protein-containing Complex Binding	SNAP Receptor Activity
	Biological Process	Intracellular Protein Transport Intra-Golgi Vesicle-mediated Transport Brain Development Regulation Of Synaptic Vesicle Priming Protein Transport Synaptic Vesicle Priming Vesicle-mediated Transport Neuron Differentiation Protein-containing Complex Disassembly Synaptic Transmission, Glutamatergic SNARE Complex Disassembly Apical Protein Localization Membrane Fusion	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Vesicle Fusion Protein Transport Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Inter-Golgi Cisterna Vesicle-mediated Transport
Pathways		COPII-mediated vesicle transport Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	COPI-mediated anterograde transport Intra-Golgi traffic
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		23 interacting genes: APP BNIP1 DSCAM FURIN GNA12 GOSR1 GOSR2 HSPB1 HUNK NSF RIPK4 RTN4 SLC6A9 SNAP23 SNAP25 STX12 STX1A STX4 STX5 STX7 STX8 TRPC3 VAMP8	9 interacting genes: ACKR5 APP EBI3 GABARAPL2 NAPA NSF SNAP25 STX5 USO1
Entrez ID		8775	9527
HPRD ID		04447	04936
Ensembl ID		ENSG00000105402	ENSG00000108587
Uniprot IDs		P54920	E9PCW1 O95249
PDB IDs
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity SNARE Complex Organelle Membrane Fusion Membrane Fusion Organelle Fusion Vesicle Fusion SNARE Binding Membrane Organization Organelle Localization By Membrane Tethering Vesicle Organization Membrane Docking Vesicle Docking Vesicle-mediated Transport Establishment Of Localization In Cell Chloride Channel Inhibitor Activity Protein Transport Syntaxin Binding Establishment Of Protein Localization Secretion By Cell Endomembrane System Intracellular Protein Localization Organelle Localization Intracellular Transport Vesicle Neuron Projection Secretion Exocytosis Intracellular Protein Transport SNARE Complex Assembly Recycling Endosome Cellular Localization Golgi Vesicle Transport Plasma Membrane Endosome Organelle Organization Membrane Neurotransmitter Transport Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Intra-Golgi Vesicle-mediated Transport Regulation Of Protein Localization Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Neuron Recognition Modulation Of Chemical Synaptic Transmission Positive Regulation Of Chemotaxis Positive Regulation Of Synaptic Transmission Positive Regulation Of Regulated Secretory Pathway Protein-containing Complex Organization Heparan Sulfate Binding Regulation Of Protein Localization To Cell Periphery	SNARE Binding Membrane Fusion Golgi Vesicle Transport Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport SNARE Complex Disassembly Vesicle Docking Membrane Organization Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Organelle Membrane Fusion Regulation Of Protein Catabolic Process Establishment Of Localization In Cell Syntaxin-1 Binding Organelle Fusion Synaptic Vesicle Priming Protein-containing Complex Disassembly Secretory Granule Localization Protein Transport Intracellular Protein Transport Positive Regulation Of Protein Catabolic Process Intracellular Transport SNAP Receptor Activity Golgi Stack Dendritic Shaft Establishment Of Protein Localization Golgi Apparatus SNARE Complex Syntaxin Binding Protein-containing Complex Organization Amyloid-beta Complex Growth Cone Lamellipodium Chemical Synaptic Transmission Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Localization Vesicle Organization ER To Golgi Transport Vesicle Membrane Golgi Vesicle Docking Trans-synaptic Signaling Synaptic Signaling Positive Regulation Of Type II Interferon Production Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Intracellular Protein Localization Interleukin-27 Receptor Binding Associative Learning
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