SNAP23 and STXBP5

Number of citations of the paper that reports this interaction (PubMedID 12832401)
0

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SNAP23	STXBP5
Description		synaptosome associated protein 23	syntaxin binding protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Cilium Membrane Phagocytic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Synapse Extracellular Exosome Tertiary Granule Membrane Presynapse	Cytoplasm Cytosol Plasma Membrane Acetylcholine-gated Channel Complex Synaptic Vesicle Membrane Cytoplasmic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Synapse Extrinsic Component Of Neuronal Dense Core Vesicle Membrane Hippocampal Mossy Fiber To CA3 Synapse Presynapse
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	GTPase Activator Activity Syntaxin-1 Binding Syntaxin Binding Myosin II Binding
	Biological Process	Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Membrane Fusion	Exocytosis Golgi To Plasma Membrane Transport Regulation Of Synaptic Vesicle Priming Protein Transport Regulation Of Exocytosis Positive Regulation Of Exocytosis Regulation Of Synaptic Vesicle Exocytosis
Pathways		ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation RHOA GTPase cycle RHOB GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Bronchopulmonary dysplasia ( 23897914) Factor VIII levels ( 30586737) Heel bone mineral density x serum urate levels interaction ( 34046847) Low vWF levels ( 26486471) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Plasma plasminogen activator levels ( 24578379) Systolic blood pressure ( 30224653) Venous thromboembolism ( 31420334) vWF levels ( 20231535 30586737) White blood cell count ( 32888494)
Interacting Genes		33 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCARB1 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P	3 interacting genes: SNAP23 STX1A STX4
Entrez ID		8773	134957
HPRD ID		03962	06845
Ensembl ID		ENSG00000092531	ENSG00000164506
Uniprot IDs		A8K287 O00161	A0A9L9PXY2 H0Y332 Q5T5C0
PDB IDs		1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		SNARE Complex SNAP Receptor Activity Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Organelle Fusion SNARE Binding Exocytosis Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Protein Transport Establishment Of Protein Localization Vesicle-mediated Transport Secretion By Cell Vesicle Organization Secretion Membrane Organization Establishment Of Localization In Cell Intracellular Protein Localization SNARE Complex Assembly Syntaxin Binding Organelle Localization Intracellular Protein Transport Regulation Of Exocytosis Cellular Localization Intracellular Transport Regulation Of Synaptic Vesicle Priming Regulation Of Vesicle-mediated Transport Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Regulation Of Secretion By Cell Regulated Exocytosis Calcium-ion Regulated Exocytosis Endomembrane System Regulation Of Secretion Zymogen Granule Membrane Phagocytic Vesicle Positive Regulation Of Exocytosis Neutrophil Degranulation Regulation Of Histamine Secretion By Mast Cell Vesicle-mediated Transport In Synapse Neuron Projection Recycling Endosome Membrane Secretory Granule Regulation Of Hormone Secretion Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Regulation Of Regulated Secretory Pathway Synaptic Vesicle Exocytosis Synaptic Vesicle Membrane	SNARE Complex SNAP Receptor Activity Organelle Membrane Fusion Vesicle Fusion Organelle Fusion Membrane Fusion SNARE Complex Assembly Exocytosis Specific Granule Vesicle Organization Neuron Projection Secretion By Cell Positive Regulation Of Regulated Secretory Pathway Secretion Regulation Of Hormone Levels Vesicle Docking SNARE Binding Membrane Organization Organelle Localization By Membrane Tethering Phagocytic Vesicle Membrane Positive Regulation Of Exocytosis Membrane Docking Hormone Secretion Schaffer Collateral - CA1 Synapse Neurotransmitter Transport Hormone Transport Synapse Regulation Of Regulated Secretory Pathway Myosin Head/neck Binding Sphingomyelin Phosphodiesterase Activator Activity Positive Regulation Of Synaptic Transmission Protein Transport Signal Release Regulation Of Insulin Secretion Vesicle-mediated Transport Positive Regulation Of Eosinophil Degranulation Storage Vacuole Regulation Of Exocytosis Regulation Of Peptide Hormone Secretion Establishment Of Protein Localization Protein-containing Complex Assembly Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Neuron Projection Membrane Protein-containing Complex Organization Regulation Of Hormone Secretion Regulation Of Protein Secretion Endomembrane System Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?