B4GALT2 and KLK13

		B4GALT2	KLK13
Description		beta-1,4-galactosyltransferase 2	kallikrein related peptidase 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Golgi Apparatus Membrane Golgi Cisterna Membrane	Extracellular Region Extracellular Space Cytoplasm Secretory Granule
	Molecular Function	Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity N-acetyllactosamine Synthase Activity Lactose Synthase Activity Protein Binding Galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Metal Ion Binding	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Brain Development Memory Locomotory Behavior Visual Learning Cerebellar Purkinje Cell Layer Development Glycosylation	Proteolysis Protein Processing Protein Maturation
Pathways		Keratan sulfate biosynthesis N-Glycan antennae elongation	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Formation of the cornified envelope
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576)	Blood protein levels ( 30072576)
Interacting Genes		13 interacting genes: ADGRB2 DES GPR35 GUCA2B ITSN2 KLK13 MAGOH MATN1 MEOX2 PFDN6 SLC39A14 TRIM63 USO1	4 interacting genes: A2M B4GALT2 SERPINA3 SERPINF2
Entrez ID		8704	26085
HPRD ID		04928	05693
Ensembl ID		ENSG00000117411	ENSG00000167759
Uniprot IDs		O60909	M0R218 Q5BQ99 Q86VI7 Q9UKR3
PDB IDs
Enriched GO Terms of Interacting Partners?		Contractile Muscle Fiber	Platelet Alpha Granule Lumen Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity Blood Microparticle Acute-phase Response Endopeptidase Inhibitor Activity Extracellular Matrix Acute Inflammatory Response Protease Binding Negative Regulation Of Complement Activation, Lectin Pathway Interleukin-8 Binding Lactose Synthase Activity N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Tumor Necrosis Factor Binding Interleukin-1 Binding Negative Regulation Of Plasminogen Activation Galactosyltransferase Activity Fibrinogen Complex Extracellular Space System Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Cerebellar Purkinje Cell Layer Development Negative Regulation Of Fibrinolysis Negative Regulation Of Complement Activation Regulation Of Fibrinolysis Regulation Of Plasminogen Activation Regulation Of Complement Activation Maintenance Of Gastrointestinal Epithelium Inflammatory Response Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Blood Coagulation Fibrinolysis Negative Regulation Of Protein Processing Negative Regulation Of Protein Maturation Positive Regulation Of Collagen Biosynthetic Process Extracellular Exosome Extracellular Region Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Positive Regulation Of Coagulation Epithelial Structure Maintenance Regulation Of Collagen Biosynthetic Process Regulation Of Collagen Metabolic Process Regulation Of Systemic Arterial Blood Pressure Growth Factor Binding Regulation Of Humoral Immune Response Negative Regulation Of Blood Coagulation
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