STX16 and VTI1A

Number of citations of the paper that reports this interaction (PubMedID 11839770)
63

Data Source:
HPRD (in vivo)

		STX16	VTI1A
Description		syntaxin 16	vesicle transport through interaction with t-SNAREs 1A
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Cytosol Focal Adhesion Endomembrane System Membrane Synaptic Vesicle Membrane SNARE Complex Golgi Cisterna Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Golgi Membrane Cytoplasm Endosome Autophagosome Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Synaptic Vesicle Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane Clathrin-coated Vesicle SNARE Complex Cytoplasmic Vesicle Late Endosome Membrane Trans-Golgi Network Membrane Neuronal Cell Body Neuron Projection Terminus Perinuclear Region Of Cytoplasm Bounding Membrane Of Organelle
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Protein Transport Vesicle-mediated Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Vesicle Docking	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Autophagy Protein Transport Vesicle-mediated Transport Endosomal Transport Macroautophagy Endocytic Recycling Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Voluntary Musculoskeletal Movement Membrane Fusion
Pathways		Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases		Pseudohypoparathyroidism
GWAS		Cardiovascular risk factors (age interaction) ( 20838585) Hemoglobin ( 32888494)	Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Carotid intima media thickness ( 30510157) Cognitive decline (age-related) ( 28078323) Colorectal cancer ( 25105248 26965516 30529582) Colorectal cancer or advanced adenoma ( 30510241) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Evening vs. morning chronotype (sMEQ score) ( 32579418) Heel bone mineral density ( 30598549) Heel bone mineral density x serum urate levels interaction ( 34046847) Hypertrophic cardiomyopathy ( 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Lung cancer ( 23143601) Multiple sclerosis ( 23412934) Non-glioblastoma glioma ( 28346443 26424050) Non-small cell lung cancer ( 31326317) QRS duration ( 27659466 30679814 31251759 27577874) Refractive error ( 32231278)
Interacting Genes		13 interacting genes: DOCK1 MEOX2 NAPB PTPN12 RHOU STX1A STX2 STX4 STX6 VAMP3 VAMP4 VPS45 VTI1A	3 interacting genes: ST3GAL3 STX16 TMBIM6
Entrez ID		8675	143187
HPRD ID		04718	18290
Ensembl ID		ENSG00000124222	ENSG00000151532
Uniprot IDs		B4DJX9 O14662	A0A994J5N6 Q96AJ9
PDB IDs		8QQF
Enriched GO Terms of Interacting Partners?		SNARE Complex SNAP Receptor Activity Organelle Fusion Vesicle-mediated Transport Vesicle Fusion Organelle Membrane Fusion SNARE Complex Assembly Vesicle Docking SNARE Binding Membrane Fusion Vesicle Organization Intracellular Protein Transport Organelle Localization By Membrane Tethering Membrane Docking Protein Transport Intracellular Transport Endomembrane System Establishment Of Protein Localization Membrane Organization Cellular Localization Establishment Of Localization In Cell Phagocytic Vesicle Intracellular Protein Localization Trans-Golgi Network Membrane Synaptic Vesicle To Endosome Fusion Vesicle-mediated Transport To The Plasma Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Cornified Envelope Assembly Endosome Exocytosis Organelle Localization Cellular Response To Type II Interferon Endocytic Recycling Clathrin-coated Vesicle Regulation Of Synaptic Vesicle Priming Localization Within Membrane Endosomal Transport Glutamatergic Synapse Golgi Vesicle Transport Retrograde Transport, Endosome To Golgi Response To Type II Interferon Post-Golgi Vesicle-mediated Transport Golgi Membrane Bounding Membrane Of Organelle Cytosolic Transport Synaptic Vesicle Organelle Organization Secretion By Cell Presynaptic Active Zone Membrane Calcium-ion Regulated Exocytosis	Ganglioside Biosynthetic Process Via Lactosylceramide Beta-galactoside (CMP) Alpha-2,3-sialyltransferase Activity N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Negative Regulation Of Calcium Ion Transport Into Cytosol Endoribonuclease Inhibitor Activity Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of IRE1-mediated Unfolded Protein Response Golgi Membrane Sialyltransferase Activity Ganglioside Metabolic Process Keratan Sulfate Proteoglycan Biosynthetic Process Oligosaccharide Biosynthetic Process Ganglioside Biosynthetic Process Keratan Sulfate Proteoglycan Metabolic Process Cellular Response To Unfolded Protein Regulation Of Cellular Response To Hypoxia Negative Regulation Of Cellular Response To Hypoxia Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of IRE1-mediated Unfolded Protein Response Response To L-glutamate Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cytosolic Calcium Ion Concentration IRE1-mediated Unfolded Protein Response Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Immunoglobulin Production Golgi Cisterna Viral Protein Processing Cellular Response To Topologically Incorrect Protein Negative Regulation Of RNA Splicing Glycosphingolipid Biosynthetic Process Protein O-linked Glycosylation Via N-acetyl-galactosamine Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response SNAP Receptor Activity Negative Regulation Of Calcium Ion Transmembrane Transport
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